Søgeresultater - Yanting Lin

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  1. 1
    Hydroxyethyl starch-curcumin nanoparticles ameliorate DSS-induced ulcerative colitis in mice via synergistic TLR4/NF-κB suppression, Nrf2 activation, intestinal barrier restoration, and gut microbiota modulation

    Hydroxyethyl starch-curcumin nanoparticles ameliorate DSS-induced ulcerative colitis in mice via synergistic TLR4/NF-κB suppression, Nrf2 activation, intestinal barrier restoration... af Sheng Li, Shiyi Lu, Jiahui Xiong, Liang Chen, Yanting Lin, Xiaohui Chen, Xinyi Wang, Lijing Lin, Xiaoliang Cai, Xiaoyu Yang

    Udgivet 2025-07-01

    Here, we systematically evaluated the therapeutic efficacy and mechanisms of action of in-house synthesized hydroxyethyl starch-curcumin nanoparticles (HES-CUR NPs) in ulcerative colitis (UC). Using a dextran sodium sulfate (DSS)-induced UC mouse model, we analyzed the effect of HES-CUR NPs on colon...

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  2. 2
    ACSL4 knockdown inhibits colorectal cancer progression through stimulating anti-tumor immunity

    ACSL4 knockdown inhibits colorectal cancer progression through stimulating anti-tumor immunity af Yiming Liu, Xingyu Jiang, Dongquan Jing, Yanting Lin, Rui Gao, Qixiang Zhao, Huijuan Da, Yiming Ren, Qiuhua Cao, Ning Liu, Xiaoyun Han, Juan Du, Xinghua Gao

    Udgivet 2025-09-01

    Background: Long-chain acyl-CoA synthetase 4 (ACSL4), a crucial modulator of ferroptosis, is associated with tumor progression, though its impact on colorectal cancer (CRC) immune dynamics is not fully understood.Methods: ACSL4 expression was analyzed in CRC tissues and correlated with patient progn...

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  3. 3
    Muscle‐Derived Small Extracellular Vesicles Mediate Exercise‐Induced Cognitive Protection in Chronic Cerebral Hypoperfusion

    Muscle‐Derived Small Extracellular Vesicles Mediate Exercise‐Induced Cognitive Protection in Chronic Cerebral Hypoperfusion af Huawei Lin, Lianhua Yin, Weilin Liu, Rui Li, Tao Jiang, Minguang Yang, Yajun Cao, Sinuo Wang, Yan Yu, Cong Chen, Xiaoqin Guo, Wenju Wang, Huanhuan Liu, Yaling Dai, Jiamin Yan, Yanting Lin, Yanyi Ding, Chendong Ruan, Lei Yang, Tiecheng Wu, Jing Tao, Lidian Chen

    Udgivet 2025-07-01

    Abstract Physical exercise protects against cognitive impairment caused by chronic cerebral hypoperfusion (CCH). However, the mechanisms through which exercise sends signals from the periphery to the central nervous system remain incompletely understood. This study demonstrated that exercise promote...

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