Search Results - Yang Zhang

Monoclonal antibodies (mAbs) and their derivatives have emerged as one of the most important classes of biotherapeutics in recent decades. The success of mAb is due to their high versatility, high target specificity, excellent clinical safety profile, and efficacy. Antibody discovery, the most upstr...

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Good ESG and enterprise innovation performance are significant drivers of high-quality economic development. Utilizing data from A-share listed companies in Shanghai and Shenzhen from 2009 to 2022, this paper employs regression analysis to explore the impact of ESG performance on enterprise innovati...

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Ice slurry ingestion is a simple cooling intervention purported to improve endurance performance. Despite its popularity in the fi eld, a recent meta-analysis suggested this intervention has no performance eff ect. The aim of the present meta-analysis was to determine the eff ect of ice slurry ing...

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Packing density is a basic property of substances and acts as one of important decisive factors of service performances. This work focuses upon the determining factors of packing density at the premise of CHON-containing isomers with the same chemical composition. It is found that, for a group of CH...

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H13 steel, a widely used material in hot work tooling, faces premature failure due to insufficient hardness and wear resistance. To address this limitation, Mo₂FeB₂ cermet coatings were fabricated on H13 alloy steel via plasma spray welding, and subseque...

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Differential scanning calorimetry (DSC) test is capable of providing comprehensive data of peak temperature (Tp, K) and onset temperature (To, K) at various heating rates (β) and widely applied in the thermal safety assessment of energetic materials (EMs). However, Tp and To (Tp/o) are variable, dep...

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ABSTRACT Objective To investigate the association between early spontaneous blood pressure (BP) reductions after thrombectomy, without pharmacological intervention, and clinical outcomes in patients with acute anterior circulation large vessel occlusion (LVO) stroke. Methods Consecutive patients wit...

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As a bearing space for urban social-ecological systems, industrial brownfields have exposed dual vulnerabilities in the social and ecological sectors. Therefore, this study introduces social-ecosystem resilience theory, which is pivotal for transforming industrial brownfields into a more resilient a...

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Damage to the spinal cord results in malfunction of sympathetic pathways, which consequently influences thermoregulation during exercise. A consensus view is that athletes with spinal cord injury (SCI) are at a heightened thermal strain than the able-bodied athletes. However, a number of studies ha...

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At present, there are few reports on the application of forging compound forming technology to mechanical calipers.Hence, the casting and forging compound forming of A356-CrV new aluminum alloy mechanical caliper samples were carried out with different casting temperatures, holding time and forging...

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Objective: Suicide attempts (SA) are common in elderly patients with major depressive disorder (MDD), but few studies have focused on the prevalence and associated factors in elderly Chinese Han patients with MDD. Method: A total of 266 first episode and drug naïve older patients with MDD (age ≥ 50 ...

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This short report discusses two deaths that occurred on October 20th 2019 during half-marathons in People’s Republic of China. The two fatal events were reported to be the consequence of sudden cardiac death. In September 2019, the State Council of China called for nationwide mass sports participa...

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Cadmium (Cd) intake is harmful to human health and Cd contamination in rice grains represents a severe threat to those consuming rice as a staple food. Knockout of Cd transporters is a promising strategy to reduce Cd accumulation in rice grains. OsNRAMP5 is the major transporter for Cd and manganese...

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ObjectiveAs an important urban public open space, park green spaces bear multiple social functions such as ecology, recreation, and culture. Park services are evolving from being low-frequency and periodic to high-frequency and all-day, giving rise to the urgent need of the public for high-quality a...

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In the context of electric bus route operations, the introduction of wireless charging facilities significantly impacts the operational scheduling of bus fleets. This study focuses on a single bus route and proposes a joint optimization model for determining departure frequencies and charging statio...

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Objective To identify the key immune-related genes and potential drug targets of Krabbe disease by using neural stem cells(NSCs) derived from induced pluripotent stem cells(iPSCs) generated from patients with Krabbe disease. Methods 1)The transcriptome data of GLD-NSCs(GSE212512) was analyzed using...

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To elucidate the effects of iron ore tailings (IOTs) and basalt fiber (BF) on the durability of recycled aggregate concrete (RAC) with different recycled aggregate replacement rates, this study used IOTs to replace natural sand at mass replacement rates of 0%, 20%, 40%, 60%, 80%, and 100% and incorp...

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Gear contact behavior significantly influences system vibration, wear, and transmission efficiency. Among the factors governing this, contact deformation, flash temperature, and meshing stiffness are particularly critical. For complex tooth surfaces, especially under localized contact conditions, on...

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Recent studies have highlighted the advantageous applications of the Marangoni effect in interfacial propulsion systems. Among these, optically driven Marangoni systems are particularly promising owing to their precise controllability and eco-friendly operation. Nevertheless, among these actuators,...

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Lung ultrasonography (LUS) is being increasingly utilized in emergency and critical settings. We performed a systematic review of the current literature to compare the accuracy of LUS and chest radiography (CR) for the diagnosis of adult community-acquired pneumonia (CAP). We searched in Pub Med, EM...

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