Suchergebnisse - Yan Zhao

The issue of antibiotic resistance caused by antibiotic resistance genes (ARGs) has become a significant concern in environmental research in recent years, while raw milk is an important link in the food chain and has become one of the carriers and reservoirs of ARGs, which has not been taken seriou...

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BackgroundThe ratio of C-reactive protein to high-density lipoprotein cholesterol (CRP/HDL-c) reflects systemic inflammation and lipid status, both of which are implicated in uric acid metabolism. This study aimed to investigate the association between CRP/HDL-c and the prevalence of hyperuricemia (...

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The discovery of microbial communities residing within tumors has unveiled a new dimension of cancer biology. In lung cancer, the intratumoral microbiome—comprising bacteria, fungi, and viruses—has emerged as a critical modulator of tumorigenesis, immune evasion, therapeutic response, and metastasis...

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Excessive dependence on Conversational artificial intelligence (CAI) can significantly impact individual adaptation and development. Given the growing need for empirical assessment, this study presents the development and psychometric validation of the CAI Dependence Scale (CAIDS), a new instrument...

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This study aimed to use Raman spectroscopy to identify the producing areas of peanut oil and build a robust discriminant model to further screen out the characteristic spectra closely related to the origin. Raman spectra of 159 peanut oil samples from different provinces and different cities of the...

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Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor. Imatinib, as a receptor-type tyrosine kinase inhibitor (TKI), becomes a first-line drug for adjuvant therapy and prognosis. However, patients are facing with the problem of primary and secondary drug resistance when using im...

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Lung cancer represents one of the most prevalent malignant tumors globally, and its treatment has entered the era of targeted therapy. The epidermal growth factor receptor (EGFR) mutation is a common type of genetic mutation in non-small cell lung cancer (NSCLC), while c-ros oncogene 1 receptor tyro...

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The West Liaohe Plain is located in the eastern Inner Mongolia, known as the golden maize belt in China, where maize acreage has continued to rise in recent years. Water is the main limiting factor for maize production in the region, therefore, this study calculated the effect of maize sowing area c...

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The influence of welding current decay time on the repair of Co-based superalloy by tungsten argon arc welding spot welding are investigated by means of simulation and experiments. The results show that: the maximum tensile stress of residual stress after welding is distributed in the center area, g...

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Microplastics (MPs) are becoming one of the most serious environmental threats worldwide. They have been shown to induce male reproductive toxicity in animal studies. However, evidence of their adverse effects on male reproductive health in human is still lacking. In this study, we evaluated the pre...

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High strength and lightweight are key trends in concrete development. Achieving a balance between these properties to produce high structural efficiency (strength-to-weight ratio) concrete is challenging due to the complex relationship between compressive strength and material components. In this st...

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<h4>Backgroud</h4>The role of maternal hypertensive disorders in pregnancy (HDP) in the development of retinopathy of prematurity (ROP) is unclear.<h4>Methods</h4>Studies were retrieved through literature searches in PubMed, EMBASE, Web of Science and the Cochrane Library up...

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Magnetic fluids (MFs) represent a unique class of smart functional lubricating materials, with their physical properties tunable by the application of a magnetic field. In this study, stable MFs were prepared with varying mass fractions of Fe3O4 nanoparticles. The influence of magnetic field on thei...

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Remarkable mechanical reinforcement of chitosan films using graphene is extremely important to greatly widen the practical application of chitosan (CS) in many fields, but there still exist challenges to regulating graphene-CS interactions for both enhanced strength and toughness. In this work, we f...

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BackgroundDue to the lack of effective treatment methods and targeted drugs, triple-negative breast cancer (TNBC) is not only difficult to treat clinically, but also has a poor prognosis for patients. This study aims to develop novel anti-TNBC drug candidates by designing 90 derivatives of 3,4-seco-...

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Plant defense responses against penetration or colonization of pathogens are mediated by activation and repression of a large array of genes. Host endogenous small RNAs are essential in gene expression reprogramming process. We identified a new Arabidopsis microRNA (miRNA) ath-miR38-3P by high-throu...

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Endoscopic submucosal dissection (ESD) has emerged as a cornerstone therapy for early-stage esophageal cancer due to its minimally invasive characterization and high efficacy. However, postoperative esophageal stricture remains a critical complication, particularly in cases involving circumferential...

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Determination of nitrogen isotopes in natural samples plays an important role in scientific exploration of the global nitrogen cycle. However, compared with carbon isotope measurement, the accuracy of nitrogen isotope ratio determination is generally lower when using the high-temperature combustion...

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Morphing wings can improve the aerodynamic performance of aircraft and expand their flight envelope. Elastic deformation of the morphing structure can enable continuous and smooth shape changes of the morphing aircraft, which is important in morphing technologies. However, airframe structures need t...

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