Search Results - Yan CHENG

Objective To investigate the effects of miR-15a on proliferation and apoptosis of human knee articular chondrocytes and explore its underlying mechanism.Methods qRT-PCR was used to detect the expression of miR-15a in normal chondrocytes and knee arthritic chondrocytes; miR-con (transfected miR-con),...

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Objective: Our study aimed to investigate the relationship between early-life famine exposure and frailty risk in later life among middle-aged and older Chinese adults, advocating for targeted early-life nutritional interventions. Method: Based on the data from the fourth wave (2017–2018) of the Chi...

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Objective(s): Asthma is a complex inflammatory disease of the lungs marked by increased infiltration of leukocytes into the airways, which restricts respiratory function. Proliferator-activated receptor-γ coactivator-1 alpha (PGC-1α) has been recognized as an essential immunomodulator and has the po...

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A total of 36 four-mon-old hybrid lambs (Dorset×Thin-tailed Han sheep) with similar body weight (BW) were randomly allocated to three dietary treatments with different energy (7.21, 10.33 and 13.49 MJ d−1 ME) but similar protein levels. The animals were slaughtered and subcutaneous fat, longissimus...

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As an auxin-responsive gene, <i>Gretchen Hagen 3</i> (<i>GH3</i>) maintains hormonal homeostasis by conjugating excess auxin with amino acids in plant stress-related signaling pathways. <i>GH3</i> genes have been characterized in many plant species, but the charac...

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The interior permanent magnet synchronous motors (IPMSMs) are extensively applied in the field of new energy vehicles due to their high-power density and excellent performance control. However, the iron loss has a significant impact on their performance. This study conducts an optimization analysis...

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BackgroundThis post hoc analysis trial compared the impacts of remimazolam and propofol anesthesia on sleep quality and fatigue after hysteroscopic surgery.MethodsThe post hoc analysis excluded patients with a Pittsburgh Sleep Quality Index (PSQI) score &gt;15 or incomplete data. Preoperative PS...

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In the era of combined antiretroviral therapy, around 50% of chronic HIV (+) individuals show varying degrees of memory and cognitive deficiency (NeuroHIV), a phenomenon of accelerated brain aging. HIV protein transactivator of transcription (TAT) has been well-accepted as a risk factor contributing...

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Objective: The aim of this meta-analysis was to clarify the role of Interleukin-1 receptor antagonist gene (IL1-RN) Variable Number of Tandem Repeats (VNTR) polymorphism on the risk of OA by means of meta-analysis. Methods: Eligible articles were retrieved from PubMed, Web of science and Google scho...

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Background The seismic prediction and assessment technology for coalbed methane (CBM) reservoirs has undergone rapid development for over three decades, playing an indispensable role in CBM exploration. Methods This study reviews the development history and current status of core technologies within...

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Early colostrum feeding facilitates the passive transfer of immunoglobulin G (IgG), which contributes to the defensive establishment of neonates; however, the molecular mechanisms of IgG absorption in the small intestine of neonatal mammals remain largely unknown. In this study, a total of 16 neonat...

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ObjectivesThis study aims to investigate the demand for childcare services for infants aged 0–3 years among the childbearing population in China and identify its key determinants.MethodsAn online survey was conducted in Suzhou, China in August 2024 using a self-designed questionnaire. Information on...

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Hypoxia and electron-hole recombination are two obstacles limiting sonodynamic therapeutic efficacy against cancer. Herein, bismuth sulfide (Bi2S3)-titania (TiO2) heterostructure is designed based on the excellent photothermal property of Bi2S3, which could improve intratumor oxygen content through...

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Abstract Background Fat grafting has been extensively used in plastic surgery practice, yet unstable retention in the recipient site remains a significant clinical challenge. The limited tolerance of injected adipose tissue to ischemia has prompted strategies aiming at timely enhancing the vasculari...

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Abstract Adenosine signaling is a crucial immunosuppressive pathway within the tumor microenvironment, making it a promising target for cancer therapy. In this study, it is demonstrated that Globo H ceramide (GHCer), the most prevalent tumor‐associated glycosphingolipid, influences the tumor microen...

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Objective To evaluate the association between the timing of initial breastfeeding and the risk of necrotising enterocolitis (NEC) and other neonatal outcomes in very preterm infants (VPIs, &lt;32 weeks’ gestation).Design Multicentre observational cohort study.Setting Data were collected from 102...

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