Search Results - Xueyan Liu

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  1. 1

    Application of <inline-formula><tex-math notation="LaTeX">$L_{1}-L_{2}$</tex-math></inline-formula> Regularization in Sparse-View Photoacoustic Imaging Reconstruction by Mengyu Wang, Shuo Dai, Xin Wang, Xueyan Liu

    Published 2024-01-01

    Photoacoustic imaging (PAI) is an advanced technique used to reconstruct the distribution of energy absorption in tissues, even when ultrasound signals are incomplete and noisy. However, the reconstruction process is challenging due to the ill-posed nature of the problem. In order to address this ch...

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  2. 2

    Comparative Studies of Reconstruction Algorithms for Sparse-View Photoacoustic Tomography by Xueyan Liu, Shuo Dai, Xin Wang, Mengyu Wang

    Published 2023-01-01

    Inverse source reconstruction is one of the most challenging problems in photoacoustic tomography (PAT) due to its ill-posed nature. Despite the extensive work done by researchers on this problem, there is currently no universally accepted solution. Regularization methods assume a significant role i...

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  3. 3

    The dosage effects of dexamethasone on osteogenic activity andbiocompatibility of poly(lactic-co-glycolic acid)/hydroxyapatite nanofibers by Chang Li, Bo Wang, Xinchen Liu, Ziyi Pan, Chao Liu, Huayu Ma, Xueyan Liu, Lijun Liu, Chao Jiang

    Published 2019-12-01

    Poly(lactic-co-glycolic acid) (PLGA) based biomaterials have many advantages and potential applications in bone tissue engineering. Whereas, a significant problem which could not be ignored was that the acidic by-products generated during its degradation induced severe inflammatory reactions and neg...

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  4. 4

    AI-driven discovery of brain-penetrant Galectin-3 inhibitors for Alzheimer's disease therapy by Xueyan Liu, Jiexin Xu, Shuping Zheng, Yaoyao Yang, Yuchong Xie, Jinyu Liu, Jian Zhong, Huiyao Zhang, Jiajing Chen, Chaoxian Dai, Dingyan Wang, Jiewei Luo, Xiaochun Chen, Feisheng Zhong, Zu-Cheng Ye

    Published 2025-08-01

    Galectin-3 (Gal-3) has emerged as a critical regulator of neuroinflammation and a promising therapeutic target for Alzheimer's disease (AD). Nevertheless, the development of brain-penetrant small-molecule Gal-3 inhibitors poses a significant challenge. To address this, we employed an artificial...

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