Search Results - Xinyi Chen

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  1. 1

    A nonlinear polycrystalline ice elastoplastic contact model and its application. by Xiaolin Li, Ge Zhang, Xinyi Chen

    Published 2025-01-01

    With the gradual warming of the global climate, the possibility and risk of large-scale sliding and collapse disasters of glaciers, large ice sheets, and thicker ice sheets have increased. Using the discrete element numerical method to analyze glacier stability is of great importance for polar disas...

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  2. 2
  3. 3

    Comparative Analysis of the Impact of Built Environment and Land Use on Monthly and Annual Mean PM<sub>2.5</sub> Levels by Anjian Song, Zhenbao Wang, Shihao Li, Xinyi Chen

    Published 2025-06-01

    Urban planners are progressively recognizing the significant effects of the built environment and land use on PM<sub>2.5</sub> levels. However, in analyzing the drivers of PM<sub>2.5</sub> levels, researchers’ reliance on annual mean and seasonal means may overlook the monthl...

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  4. 4

    Two-dimensional NMR characterization of gas–water distribution in tight sandstone reservoirs: a case study from the Ordos Basin, China by Ran Zhang, Ran Zhang, Xinyi Chen, Xinyi Chen, Xin Sun, Xin Sun, Xiang Ge, Xiang Ge, Huanfu Du, Huanfu Du, Mengmeng Yao, Mengmeng Yao

    Published 2025-07-01

    Tight sandstone reservoirs exhibit low porosity, low permeability, significant heterogeneity, and complex gas-water distribution patterns, posing significant challenges for conventional logging methods in accurate gas reservoir identification. Incomplete comprehension of nuclear magnetic signal resp...

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  5. 5

    Analysis of the nonlinear relationships between insulin resistance indicators such as LAP and TyG and depression, and population characteristics: a cross-sectional study by Yueyu Zhang, Xinyi Chen, Yu Wang, Yi Tang, Kangrui Zhang, Juncang Wu

    Published 2025-06-01

    Abstract Background Accumulating evidence indicates a potential link between insulin resistance (IR) and depression, although the bidirectional nature and underlying mechanisms of this association remain poorly understood. This study aims to systematically investigate the associations between multip...

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  6. 6

    Longitudinal bidirectional relations between parental phubbing and adolescents’ life satisfaction: The roles of problematic social network use and personality by Xiaoyan Zhou, Fangfang Tian, Xingchao Wang, Xinyi Chen, Jiping Yang, Xueqi Zeng

    Published 2025-06-01

    Parental phubbing, as a new negative factor for adolescents’ healthy and positive development, has been noticed by scholars. The current study explored the longitudinal association between parental phubbing and adolescents’ life satisfaction across three years, taking into account adolescents’ prob...

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  7. 7

    A diagnostic model based on magnetic resonance imaging for Menière’s disease: a multicentre study by Xinyi Chen, Yanfeng Zhao, Yunchong Han, Kai Wei, Shufang Cheng, Yongjun Ye, Jie Feng, Xinchen Huang, Jingjing Xu

    Published 2025-07-01

    PURPOSE: To evaluate the diagnostic performance of delayed post-gadolinium enhancement magnetic resonance imaging (DEMRI) in diagnosing Menière’s disease (MD) and to establish an effective MRI-based diagnostic model. METHODS: This retrospective multicenter study assessed DEMRI descriptors in patien...

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  8. 8

    Elevation of ISG15 promotes diabetic kidney disease by modulating renal tubular epithelial cell pyroptosis by Lingzhi Huang, Xinyi Chen, Yawen Shao, Shujun Deng, Chen Wang, Jianqiao Chen, Yongsheng Xie, Siming Yuan, Liqin Tang

    Published 2025-06-01

    Abstract Background Fibrosis and inflammation in the renal tubular epithelial cells (TECs) are key contributors to the pathology of diabetic kidney disease (DKD). Nevertheless, the precise triggers of these processes remain unclear. This study aimed to explore the role of interferon‐stimulated gene...

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  9. 9

    Threshold Effects of Nitrogen Fertilization Rates on Growth and Essential Oil Yield with Component Regulation in <i>Cinnamomum camphora</i> var. <i>linaloolifera</i> by Zhirong Liu, Xinyi Chen, Jiao Zhao, Luyuan Sun, Jian Guo, Yangyang Shao, Jia Liu, Lei Zhong, Haiyan Zhang, Yanbo Wang, Jie Zhang

    Published 2025-06-01

    The determination of an optimal nitrogen (N) fertilization rate is critical for the sustainable large-scale cultivation of <i>Cinnamomum camphora</i> var. <i>linaloolifera</i> for essential oil production. Both suboptimal and excessive nitrogen inputs can adversely affect pla...

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  10. 10

    Pectinase responsive nanoplatform for oral targeted delivery 5-aminosalicylic acid and zinc coordination driven nanozyme in inflammatory bowel disease treatment by Yiting Lin, Siqi Fang, Xinyi Chen, Xiang Li, Xinlin Zhao, Yanwen Wang, Jing Lu, Qingdong Ji, Shuhui Zheng, Jiafeng Zou, Chendong Qi, Feng Gao

    Published 2025-12-01

    Characterized by weight loss, intestinal ulcerations, and diarrhea with blood or mucus, inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, is a chronic gastrointestinal condition. The rising incidence of IBD is placing pressure on healthcare systems globall...

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  11. 11

    Latency-Associated Nuclear Antigen (LANA) Promotes Ferroptosis by Suppressing Nrf2/GPX4 and Upregulating MDM2 by Yuejia Cao, Shihan Shao, Yingying Zhang, Dandan Song, Fei Gui, Xinyi Chen, Yu Hong, Rong Chen, Yang Song, Dongmei Li, Xiaohua Tan, Chunhong Di

    Published 2025-06-01

    Ferroptosis, an iron-dependent cell death driven by lipid peroxidation, is regulated by key mediators including glutathione peroxidase 4 (GPX4) and nuclear factor erythroid 2-related factor 2 (Nrf2). Kaposi’s sarcoma-associated herpesvirus (KSHV) encodes latency-associated nuclear antigen (LANA), a...

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  12. 12

    Parylene-C Modified OSTE Molds for PDMS Microfluidic Chip Fabrication and Applications in Plasma Separation and Polymorphic Crystallization by Muyang Zhang, Haonan Li, Xionghui Li, Zitong Ye, Qinghao He, Jie Zhou, Jiahua Zhong, Hao Chen, Xinyi Chen, Yixi Shi, Huiru Zhang, Lok Ting Chu, Weijin Guo

    Published 2025-06-01

    This work presents a novel microfabrication process that addresses the interference of thiol groups on off-stoichiometry thiolene (OSTE) surfaces with the curing of polydimethylsiloxane (PDMS) by integrating the high-performance polymer Parylene-C. The process utilizes a Parylene-C coating to encaps...

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  13. 13

    CRISPR/Cas9-Mediated Knockout of the <i>Corazonin</i> Gene Indicates Its Regulation on the Cuticle Development of Desert Locusts (<i>Schistocerca gregaria</i>) by Yingying He, Qiang Yan, Yong Bi, Guosheng Liu, Shuang Hou, Xinyi Chen, Xiaoming Zhao, Xueyao Zhang, Min Zhang, Jianzhen Zhang, Binbin Ma, Benjamin Warren, Siegfried Roth, Tingting Zhang

    Published 2025-07-01

    The desert locust (<i>Schistocerca gregaria</i>) represents one of the most destructive agricultural pests globally, renowned for its ability to form massive swarms that can devastate crops and threaten food security across vast regions. Despite the widespread application of the CRISPR/C...

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  14. 14

    Gradient Nanostructures and Machine Learning Synergy for Robust Quantitative Surface‐Enhanced Raman Scattering by Xiaoyu Zhao, Yuxia Wang, Yuting Liu, Xinyi Chen, Mingyu Cheng, Yaxin Wang, Jiahong Wen, Renxian Gao, Kun Zhang, Fengyi Zhang, Rufei Cui, Yongjun Zhang, Zengyao Wang, Bin Ai

    Published 2025-07-01

    Abstract Surface‐Enhanced Raman Scattering (SERS) holds significant promise for trace‐level molecular detection but faces challenges in achieving reliable quantitative analysis due to signal variability caused by non‐uniform “hot spots” and external factors. To address these limitations, a novel SER...

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  15. 15

    Engineered red blood cell extracellular vesicles for delivery of Dox and siIDO1 enhance targeted chemo-immunotherapy of acute myeloid leukemia by Jing Yang, Ling Zhang, Nan Wu, Jiayuan Hu, Jun Ren, Xinyi Chen, Xingyu Wei, Minghui Sun, Ziwei Li, Yongcan Liu, Yan Shu, Genyou Li, Fangfang Jin, Can Lin, Lisha Tang, Zesong Yang

    Published 2025-07-01

    Background As a malignancy of hematopoietic origin, the standard-of-care cytoreductive chemotherapy can not provide satisfactory treatment effect for patients with acute myeloid leukemia (AML). Immunotherapy has received increasing attention in leukemia treatment. However, the immunosuppressive micr...

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