Search Results - Xingyu Han

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    Integrated proteomic and metabolomic profiling identifies distinct molecular signatures and metabolic pathways associated with obesity and potential targets for anti-obesity therapies

    Integrated proteomic and metabolomic profiling identifies distinct molecular signatures and metabolic pathways associated with obesity and potential targets for anti-obesity therap... by Yi Li, Yi Li, Huawu Yang, Xinpeng Zhang, Xingyu He, Anke Liuli, Rui Li, Xingyu Han, Yongmei Li, Pan Gao

    Published 2025-07-01

    BackgroundAdipose tissue remodeling induced by bariatric surgery plays a pivotal role in promoting weight loss and metabolic improvement. However, the underlying molecular mechanisms, particularly protein-metabolite regulatory networks, remain poorly understood. This integrative proteomic and metabo...

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    FBXL3 serves as a suppressor of regenerative myogenesis

    FBXL3 serves as a suppressor of regenerative myogenesis by Wei He, Wei He, Shiyuan Han, Yanming Wu, Min Chen, Ting Xue, Hua You, Ying Chang, Song-Bai Liu, Yi Sun, Yinjiang Tang, Xinghong Shi, Xingyu Han, Zixin Ma, Panting Qian, Sha Geng, Chaofan Wu, Yating Liang, Yangxin Li, Yan Xu, Yao-Hua Song, Yao-Hua Song

    Published 2025-07-01

    Muscle regeneration hinges on the proliferation and differentiation of satellite cells. FBXL3, a member of the F-box protein family known for its role as a negative regulator of the circadian clock, is implicated in myogenesis. In this study, we demonstrate the expression of FBXL3 in satellite cells...

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