Search Results - Xin-Xin Zhang
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Melatonin as an anti-inflammatory hormone bridging migraine relief and cancer immunity enhancement: a literature review
Published 2025-07-01Get full textMelatonin, once relegated to the circadian periphery, has resurfaced as a pleiotropic immunomodulator capable of quelling neurogenic inflammation while invigorating antitumour defence. Migraine—and its disabling, episodic neurovascular pain—shares an “inflammatory genome”, defined here as a conserve...
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METTL3 promotes peritoneal metastasis of colorectal cancer through regulating m6A modification of NRXN3 mRNA
Published 2025-08-01Get full textSummary: Colorectal cancer (CRC) is a prevalent digestive system malignancy accompanied by peritoneal metastasis occurring in 7% of cases. Methyltransferase-like 3 (METTL3) promoted the progression of CRC whereas its function in peritoneal metastasis was incompletely understood. Here, we found that...
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Placental RTN3L‐dependent ER‐Phagy Contributes to Fetal Testicular Dysplasia Upon Environmental Stress
Published 2025-07-01Get full textAbstract Prenatal environmental stress damages fetal testicular development, leading to male infertility. However, the precise mechanisms underlying the impact of gestational environmental stress on fetal testicular development require further investigation. This study demonstrates that gestational...
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