Search Results - Xiaowei CHEN

IntroductionInteractive installation art offers immersive and participatory environments that elicit complex and multidimensional emotional experiences—encompassing sensorimotor engagement, affective resonance, and cognitive reflection. However, these emotional responses’ inherently dynamic, subject...

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High-altitude pulmonary edema (HAPE) is a severe condition associated with high-altitude environments, and its molecular mechanism has not been fully elucidated. This study systematically analyzed the DNA methylation status of HAPE patients and healthy controls using reduced-representation bisulfite...

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Weissella cibaria M165 with a mulberry fruit wine histamine degradation ability was selected as the research object, and the key histamine degradation enzyme of W. cibaria M165 was revealed. The potential key histamine degradation enzyme gene (glyceraldehyde 3-phosphate dehydrogenase gene) of W. cib...

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Investigating the functional interactions between rumen microbial fermentation and epithelial mitochondrial dynamics/energy metabolism in Tibetan sheep at different altitudes, this study examined ultrastructural changes in rumen epithelial tissues, expression levels of mitochondrial dynamics-related...

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By cultivating diverse plants on a same land, intercropping can enhance soil organic carbon (SOC) sequestration and crop production efficiency. However, the impact of different intercropping practice on SOC mineralization and its stability under global climate change remains limited. Herein, an eigh...

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M1-polarized macrophages exhibit remarkable resistance to ferroptosis, a form of regulated cell death driven by excessive lipid peroxidation. Yet the underlying mechanisms remain to be defined. Through CRISPR-based functional screen of metabolic genes combining transcriptomics analysis, we herein id...

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Exogenous neural stem cell transplantation has become one of the most promising treatment methods for chronic stroke. Recent studies have shown that most ischemia-reperfusion model rats recover spontaneously after injury, which limits the ability to observe long-term behavioral recovery. Here, we us...

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<b>Background:</b> Alzheimer’s disease (AD) is the most common dementia, characterized by significant cognitive impairments and neural network dysfunction. Currently, multiple therapeutic strategies are being developed to design effective anti-AD drugs. Among them, Withaferin A (WA), a n...

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Summary: The lateral habenula (LHb) is implicated in the regulation of numerous physiological functions, particularly those associated with thermoregulation. It exhibits close anatomical and functional connections with the key brain regions that play a crucial role in regulating body temperature. Ho...

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Abstract The global trend toward aging populations has resulted in an increase in the occurrence of Alzheimer's disease (AD) and associated socioeconomic burdens. Abnormal metabolism of amyloid‐β (Aβ) has been proposed as a significant pathomechanism in AD, supported by results of recent clinic...

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