Search Results - Xiaolin Zhang

The Delboeuf illusion occurs when two circles (test figures) of equal radius are placed side by side and surrounded by concentric circles (inducers) of varying radii, resulting in the test figure being misestimated depending on the size of the surrounding inducer. This study conducted three experime...

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Objective To identify co-expressed genes and potential comorbidity mechanisms between Alzheimer′s disease(AD) and epilepsy with publicly available single-cell transcriptome sequencing data from human brains, followed by functional validation in APP/PS1 double transgenic AD mouse models expressing th...

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This study addresses challenges such as multi-scale defects, varying lighting, and irregular shapes by proposing an improved YOLOv10 model that integrates the ECA attention mechanism, RefConv feature enhancement module, and WIoU loss function for complex pavement defect detection. The RefConv dual-b...

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Aspects of urban environments, especially green spaces, are known to benefit mental health and well-being. However, the healing potential of urban third places remains underexamined compared to the well-documented benefits of more “natural” environments. “Third places” refers to public spaces where...

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BackgroundPatients with heart failure face a significantly elevated risk of cognitive impairment, yet clinical recognition remains inadequate—particularly among younger individuals and those with mild symptoms, leading to frequent underdiagnosis. The increasing prevalence among younger patients furt...

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Conclusions: This MR study establishes causal links between specific plasma lipidomes and TN risk, identifying protective lipid species and revealing a bidirectional relationship for PC, offering potential therapeutic targets for TN management.

Conclusions: The KYNA level may correspond to the underlying status of acute myocardial infarction and is a promising biomarker for predicting STEMI progression.

Purpose: To investigate the correlation of serum uric acid levels with the clinical outcomes of arthroscopic microfracture in osteochondral lesions of the talus (OLTs) and determine the cut-off point for predicting outcomes. Methods: A total of 134 OLTs patients who underwent arthroscopic microfract...

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Abstract CRISPR activation and interference (CRISPRa/i) are highly effective tools to regulate transcription by fusing dead Cas9 (dCas9) with transcriptional regulatory factors guided by small guide RNA (sgRNA) in mammalian cells and mice. Still, a controllable gene regulation system is desired to i...

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