Search Results - Xiaohong Li
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Identification of biomarkers between coronary artery disease and non-alcoholic steatohepatitis: a combination of bioinformatics and machine learning
Published 2025-07-01Get full textBackgroundNon-alcoholic steatohepatitis (NASH) commonly complicates coronary artery disease (CAD), yet the interaction mechanism remains unclear. Our research seeks to investigate the common mechanisms and key signature genes between CAD and NASH.MethodsRNA sequence information for CAD and NASH was...
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Clinical features of immunoglobulin G4-related spinal pachymeningitis
Published 2025-07-01 Get full text
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The performance of sCD25 and CTLs degranulation test for screening patients with primary hemophagocytic lymphohistiocytosis: a large-scale multicenter study in China
Published 2025-07-01Get full textBackgroundHemophagocytic lymphohistiocytosis can be classified as primary HLH (pHLH) and secondary HLH. The early identify of pHLH can facilitate successful treatment. The rapid screening test greatly facilitated the diagnostic process of pHLH. However, there are rare studies to explore the ability...
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Opportunities and Challenges of Brain-on-a-Chip Interfaces
Published 2025-01-01Get full textThe convergence of life sciences and information technology is driving a new wave of scientific and technological innovation, with brain-on-a-chip interfaces (BoCIs) emerging as a prominent area of focus in the brain–computer interface field. BoCIs aim to create an interactive bridge between lab-gro...
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Exosomal miR-320d derived from adipose tissue-derived MSCs inhibits apoptosis in cardiomyocytes with atrial fibrillation (AF)
Published 2019-12-01Get full textMicroRNAs (miRNAs) play a key role in various pathological processes like atrial fibrillation (AF), which is a common cardiac arrhythmia. Exosomes are essential information carrier in the intercellular communication. Therefore, this study aimed to investigate the effects of exosomal miR-320d on card...
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The effectiveness and safety of ofatumumab for the treatment of pemphigus vulgaris: a cohort study based on a registry database
Published 2025-07-01Get full textBackgroundOfatumumab, a fully human anti-CD20 monoclonal antibody administered subcutaneously and indicated for multiple sclerosis, might theoretically be effective for patients with pemphigus vulgaris (PV).ObjectiveTo evaluate the effectiveness and safety of ofatumumab in patients with PV.MethodsTh...
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Gait dynamics and brain function abnormalities in Parkinson’s disease with freezing of gait: a clinical study using resting-state fMRI and wearable devices
Published 2025-07-01Get full textIntroductionParkinson’s disease (PD)-associated freezing of gait (FoG) (PDFoG) refers to episodes where patients feel the urge to move but experience temporary immobility or markedly shortened steps. This leads to frequent falls and, eventually, the loss of walking ability, severely affecting patien...
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Analysis of characteristics of children with unintentional injuries admitted in Pediatric Intensive Care Unit from 2017 to 2022 in Shanghai, China
Published 2025-06-01Get full textBackground Understanding the patterns of unintentional injuries (UIs) among children admitted to the Pediatric Intensive Care Unit (PICU) is crucial for effective prevention and management. We aimed to explore the demographic, situational and clinical characteristics of children with UIs admitted to...
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Obesity, cytokines and psychopathology in patients with chronic schizophrenia
Published 2025-07-01Get full textBackgroundObesity and dysregulated cytokine levels are prevalent in schizophrenia patients undergoing antipsychotic treatment. While cytokines are implicated in obesity, their relationship with psychopathology in schizophrenia remains underexplored. This study investigated associations between body...
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Proteomic identification of potential biomarkers for cervical squamous cell carcinoma and human papillomavirus infection
Published 2017-04-01Get full textIt is known that high-risk human papillomavirus infection is the main etiological factor in cervical carcinogenesis. However, human papillomavirus screening is not sufficient for early diagnosis. In this study, we aimed to identify potential biomarkers common to cervical carcinoma and human papillom...
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