Search Results - Xiaochen Ni

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    Targeting PGK1 as a Novel strategy to regulate the sensitivity of HER2 positive gastric cancer to lapatinib by Xiaochen Ni, Kaiyuan Zhang, Xueru Huang, Mingsi Zhang, Mingsi Zhang, Jianing Guo, Wei Fan, Chuhang Wang, Zhongyan Du, Zhongyan Du, Tao Jiang, Tao Jiang, Tao Jiang, Guangji Zhang, Guangji Zhang, Guangji Zhang

    Published 2025-07-01

    HER2 is amplified in approximately 20% of gastric cancers, and these patients exhibit a favorable response to trastuzumab treatment. Lapatinib, as a HER2-targeted drug, demonstrates potent inhibitory effects on HER2-addicted N87 gastric cancer cells. However, lapatinib has not shown significant adva...

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