Search Results - Xiao Zhu

Alternative splicing (AS) is pivotal in gene expression regulation and protein diversity generation. Suppression of aberrant AS holds promise in cancer management. Utilizing zebrafish-human homologous genes, we investigated AS events across 33 tumor types from TCGA, employing Cox regression analyses...

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Background: Lung adenocarcinoma (LUAD) is characterized by low overall survival rates. This research aims to explore the association between long non-coding RNAs (lncRNAs) and chromatin histone methylation/demethylation modifiers in LUAD. Methods: Datasets from The Cancer Genome Atlas (TCGA), Molecu...

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Astaxanthin (AST) is a fat-soluble carotenoid antioxidant. AST exhibits multiple protective mechanisms, including its antioxidant, anti-inflammatory, immunomodulatory, anti-apoptotic, nervous system-protective, anti-tumor, and anti-fibrotic effects. These effects make it a promising compound for the...

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High-field asymmetric waveform ion mobility spectrometry (FAIMS) is a chemical analytical technique that utilizes the difference in ion mobility of ions at alternating high-low electric field strengths for ion separation. FAIMS has the advantages of working at atmospheric pressure, easy on-site dete...

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Lipophilic electron shuttles (ESs), such as phenazine and phenoxazine, can penetrate the outer membrane and enter the periplasmic space, mediating extracellular electron transfer reactions. This study investigates how lipophilic ESs (resazurin, a phenoxazine) regulate carbon metabolic pathways in bi...

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Objective Lambing in ewes is a complex and crucial aspect of sheep production that directly influences economic viability and production efficiency. In the present study, we analyzed the genomes of single lamb (SLE) and twin lamb (TLE) Hotan sheep to elucidate the genetic mechanisms underlying lamb...

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Chemical potassium (K) fertilizer is commonly used in apple (Malus domestica L. Borkh) production but K is easily fixed by soil, resulting in reduced K fertilizer utilization and wasted resources. K-solubilizing bacteria (KSB) can cost-effectively increase the soluble K content in rhizosphere soil....

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Accurate benchmarking of structural variant (SV) detection is essential for advancing the development and application of human whole-genome sequencing (WGS). A fundamental challenge in benchmarking SV detection results is determining whether two SVs represent the same event. Differences in the varia...

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<b>Background/Objectives:</b> Avatrombopag (AVA), a thrombopoietin receptor agonist used to treat thrombocytopenia in patients with chronic liver disease, exhibits significant pharmacokinetic (PK) variability, particularly under fasting conditions. This study investigates the combined in...

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Topping is a cultivation method that is widely practiced due to the indeterminate growth character of cotton (Gossypium hirsutum L.). Among the different methods of accomplishing topping, manual topping is common in the Yellow River Valley of China, although it is time- and labor-intensive. The obje...

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Abstract Intraoperative identification of the isocitrate dehydrogenase type 1 (IDH1) genotype, a key molecular marker in glioma, is essential for optimizing surgical strategies and tailoring post‐surgical treatments. However, current clinical practices lack effective methods for real‐time IDH1 genot...

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