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    BroadAMP-GPT: AI-Driven generation of broad-spectrum antimicrobial peptides for combating multidrug-resistant ESKAPE pathogens

    BroadAMP-GPT: AI-Driven generation of broad-spectrum antimicrobial peptides for combating multidrug-resistant ESKAPE pathogens by Yanru Li, Xianghan Xu, Xiaohui Zhang, Zhihui Xu, Jiaqi Zhao, Ruiyu Zhu, Ziyu Wang, Wei Ran, Wenqian Zhao, Ningyang Yan, Yifan Leng, Zexu Miao, Xiaomin Wang, Liping Wang, Jinxin Liu, Cong Pian, Jinhu Huang

    Published 2025-12-01

    Antimicrobial peptides (AMPs) are promising candidates to address the global antimicrobial resistance crisis, yet their traditional design remains labor-intensive and inefficient. Here, we developed BroadAMP-GPT, an integrated computational-experimental framework that combines AI-driven generation,...

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