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    Targeting the MDK/c‐Myc complex to overcome temozolomide resistance in glioma

    Targeting the MDK/c‐Myc complex to overcome temozolomide resistance in glioma by Xiaonan Xi, Xiaojing Ding, Qianqian Wang, Ning Liu, Bangmao Wang, Genbei Wang, Weilong Zhong, Yaxin Lu

    Published 2025-06-01

    Abstract Background Temozolomide (TMZ), which is an alkylating agent, is the standard chemotherapeutic drug used for glioma treatment. However, the development of resistance to TMZ limits its efficacy. Thus, identifying novel therapeutic targets is necessary. Methods In this study, the levels of mid...

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