Search Results - Wei Yi

Ferroptosis is distinctive type programmed cell death. Tumor cells, with their higher iron levels, render them more susceptible to ferroptosis Inducing ferroptosis can activate immune cells, regulate immune evasion, and inhibit the biology activity of cancer cells. Therefore, ferroptosis-induced can...

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Blast disease, caused by the hemibiotrophic ascomycete fungus, Magnaporthe oryzae, is a significant threat to sustainable rice production worldwide. Studies have shown that the blast fungus secretes vast arrays of functionally diverse proteins into the host cell for a successful disease progression....

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Accurate ubiquitination identification is crucial in biological function analysis. We developed Ubigo-X, a novel protein ubiquitination prediction tool. Our training data, sourced from the Protein Lysine Modification Database (PLMD 3.0), comprised 53,338 ubiquitination and 71,399 non-ubiquitination...

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Thyroid associated ophthalmopathy (TAO) is an autoimmune orbital disease associated with thyroid dysfunction, which may significantly impact the appearance and quality of life of patients. The course of TAO includes active stage and inactive stage, and the treatment methods are different in differen...

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China has set targets for achieving peak carbon emissions and carbon neutrality, supporting the global climate change mitigation targets. Meanwhile, after the Sustainable Development Goals (SDGs) were established in 2015, China developed a national strategy for reaching them. This study aims to reve...

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As global aging intensifies, the incidence of degenerative bone and joint diseases such as osteoarthritis bone aging and osteoporosis continues to rise. Traditional treatment methods face bottlenecks in long-term management, including drug side effects and low patient compliance. Traditional Chinese...

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Seagrass meadows are recognized for their ecological importance, yet their influence on microbial community structure remains insufficiently characterized. This study examined the effects of seagrass presence on microbial assemblages in a subtropical coastal environment by comparing seagrass habitat...

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The purpose of this study was to develop an effective and non-invasive nomogram for evaluating liver obvious inflammation in untreated HBeAg positive patients with chronic hepatitis B virus (HBV) infection. A nomogram was established on a model cohort of 292 treatment-naïve HBeAg positive patients w...

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Ubiquitin (Ub), a central regulator of protein turnover, can be phosphorylated by PINK1 (PTEN-induced putative kinase 1) to generate S65-phosphorylated ubiquitin (pUb). Elevated pUb levels have been observed in aged human brains and in Parkinson’s disease, but the mechanistic link between pUb elevat...

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Background Studies have shown acute flares of chronic hepatitis B (CHB) might be related to immunologic changes that occur during pregnancy. However, the indicators for predicting acute flares of CHB among pregnant women still need further study. We aimed to distinguish the relevance between serum l...

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Genetic diversity, population structure, and population expansion of goats worldwide (4 165 individuals from 196 breeds) were analyzed using published mitochondrial DNA (mtDNA) D_loop hypervariable region sequences. Results showed that 2 409 haplotypes and 301 polymorphic sites were present within t...

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BackgroudPapillary thyroid carcinoma (PTC) represents a malignant epithelial tumor characterized with a preference for younger individuals. Despite its generally favorable prognosis, PTC still poses considerable challenges, particularly in regards to the propensity for distant metastasis. As a key e...

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