Search Results - Wei Gong
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Gypenosides alleviates MCT-induced pulmonary arterial hypertension in rats by targeting oxidative stress, inflammation, and apoptosis
Published 2025-08-01Get full textObjective(s): Pulmonary arterial hypertension (PAH) is a severe heart-lung condition characterized by complex changes in the pulmonary vasculature, known as pulmonary vascular remodeling (PVR). Gypenosides (Gyp) possesses a range of pharmacological properties, including anti-inflammatory and anti-ox...
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Socioeconomic status and lifestyle as factors of multimorbidity among older adults in China: results from the China Health and Retirement Longitudinal Survey
Published 2025-07-01Get full textBackgroundMultimorbidity is increasingly prevalent among older adults and poses significant challenges to public health systems. While previous studies have highlighted the role of individual behaviors, the complex interaction between lifestyle factors and socioeconomic status (SES) in multimorbidit...
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Transglutaminase-modified whey protein/nanocrystalline cellulose composite films: glycerol plasticization optimization and cheese packaging application
Published 2025-09-01Get full textTo overcome the limitation of bio-based packaging films in terms of mechanical/ barrier properties and preservation of freshness in high-fat foods. This study explored the effect of glycerol content (40 %, 45 %, 50 %, 55 % and 60 %) on the properties of whey protein concentration (WPC) and nanocryst...
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Differences in parameter estimates derived from various methods for the ORYZA (v3) Model
Published 2022-02-01Get full textParameter estimation is always a difficult issue for crop model users, and inaccurate parameter values will result in deceptive model predictions. Parameter values may vary with different inversion methods due to equifinality and differences in the estimating processes. Therefore, it is of great imp...
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Structure of human glycoprotein 2 reveals mechanisms underlying filament formation and adaption to proteolytic environment in the digestive tract.
Published 2025-06-01Get full textGlycoprotein 2 (GP2) and Uromodulin (UMOD) are considered as paralogs that share high sequence similarity and have similar antibacterial functions. UMOD are abundant as filaments in the urinary tract, and a high-mannose N-glycosylation site located on the N-terminal region protruding from UMOD filam...
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Spatial–Spectral Feature Fusion and Spectral Reconstruction of Multispectral LiDAR Point Clouds by Attention Mechanism
Published 2025-07-01Get full textHigh-quality multispectral LiDAR (MSL) data are crucial for land cover (LC) classification. However, the Titan MSL system encounters challenges of inconsistent spatial–spectral information due to its unique scanning and data saving method, restricting subsequent classification accuracy. Existing spe...
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Ibrutinib targets microRNA-21 in multiple myeloma cells by inhibiting NF-κB and STAT3
Published 2018-01-01Get full textThe oncogenic microRNA-21 contributes to the pathogenesis of multiple myeloma. Ibrutinib (also referred to as PCI-32765), an inhibitor of Bruton’s tyrosine kinase, while its effects on multiple myeloma have not been well described. Here, we show that microRNA-21 is an oncogenic marker closely linked...
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Fc-Elabela mitigates heart failure without liver and renal toxicity in mice
Published 2025-07-01Get full textAimsElabela (ELA) is a ligand of the APJ receptor and exhibits anti-heart failure activities. However, the short half-life of the ELA limits its clinical applications. Our previous study recombined the short peptide ELA-21 and the Fc fragment of human IgG into a long-acting Fc-ELA-21 fusion protein...
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Arctigenin induced gallbladder cancer senescence through modulating epidermal growth factor receptor pathway
Published 2017-04-01Get full textGallbladder cancer has poor prognosis and limited therapeutic options. Arctigenin, a representative dibenzylbutyrolactone lignan, occurs in a variety of plants. However, the molecular mechanisms involved in the antitumor effect of arctigenin on gallbladder cancer have not been fully elucidated. The...
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Morphological diversity and correlation analysis of phenotypes and quality traits of proso millet (Panicum miliaceum L.) core collections
Published 2019-05-01Get full textGenetic diversity and comprehensive performance are the basis for the discovery and efficient use of proso millet (Panicum miliaceum L.) core collections. In this study, 386 proso millet core collections were used as materials to observe inflorescence color, leaf phase, inflorescence density, axis s...
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Research progress on the breeding of japonica super rice varieties in Jiangsu Province, China
Published 2017-05-01Get full textIn this study we report the results of a decade-long breeding program for japonica super rice made by Nanjing Branch of Chinese National Center for Rice Improvement in Jiangsu Academy of Agricultural Sciences. We concluded that selection of parents with good comprehensive traits and complementary ad...
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