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Integrative causal and single-cell analyses reveal genes responsive to endocrine disruptors driving human male infertility
出版 2025-09-01獲取全文Male infertility is a growing global health concern increasingly linked to environmental exposure to endocrine-disrupting chemicals (EDCs). However, the specific molecular mechanisms by which EDCs contribute to impaired reproductive function remain unclear. In this study, we systematically identifie...
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Integrative causal inference illuminates gene-environment interactions linking endocrine disruptors to female infertility
出版 2025-09-01獲取全文Female infertility, a global health concern affecting up to 12 % of women, is influenced by genetic, hormonal, and environmental factors. Among environmental contributors, endocrine-disrupting chemicals (EDCs), which interfere with hormonal systems, have gained attention for their potential impact o...
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