Hakutulokset - V. V. Grechenko
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1
Expansion of the γδT cell population in peripheral blood: a response of immune system to the damage of gastrointestinal mucous membranes in older age groups
Julkaistu 2024-11-01Hae kokotekstiγδT cells are unique lymphocytes that take an intermediate position between the cells of innate and adaptive immunity. Even at the stage of differentiation in the thymus, they acquire the status of effectors with cytotoxic activity and become powerful cytokine producers. The antigen-recognizing rece...
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Biomarkers of inflammaging in geriatric syndromes
Julkaistu 2025-06-01Hae kokotekstiThe worldwide trend towards increasing life expectancy makes relevant the studies on aging and ageassociated pathology. The pathophysiologic mechanisms underlying geriatric syndromes remain insufficiently studied. It is hypothesized that chronic sterile inflammation (inflammaging) may be a key facto...
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Hyperexpression of TLR2 and TLR4 in patients with ischemic stroke in acute period of the disease
Julkaistu 2020-08-01Hae kokotekstiPathogenesis of ischemic stroke is actively involved in the system of innate immunity. Under conditions of cerebral ischemia, a number of biologically active substances are released that interact with innate immunity receptors, in particular TLR2 and TLR4, which exacerbate inflammation...
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CHANGES OF INNATE IMMUNITY INDEXES IN SEVERE ASTHMA IN CHILDREN
Julkaistu 2019-01-01Hae kokotekstiAt the present time, the role of innate immunity in pathogenesis of bronchial asthma (BA) is actively studied, in particular, significance of TLRs and cytokines. The study included 42 patients with severe bronchial asthma (from 3 to 12 years old), and 67 healthy children at the same age. Expression...
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