Search Results - V. S. Pykhtina

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  1. 1
    RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM AND REPLICATIVE CELLULAR SENESCENCE: THEIR INTERACTION DURING THE VASCULAR AGEING

    RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM AND REPLICATIVE CELLULAR SENESCENCE: THEIR INTERACTION DURING THE VASCULAR AGEING by V. S. Pykhtina, I. D. Strazhesko, M. V. Agaltsov, O. N. Tkacheva

    Published 2015-09-01

    The problem of vascular aging is discussed. Special attention among the signs of vascular aging is paid to the activation of the renin-angiotensin-aldosterone system as a source of chronic inflammation and oxidative stress, as well as to its relation to replicative cellular senescence. Potential rou...

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  2. 2
    AGE-RELATED LEFT VENTRICLE MYOCARDIAL REMODELING: IS THERE A LINK WITH NORMAL AGEING?

    AGE-RELATED LEFT VENTRICLE MYOCARDIAL REMODELING: IS THERE A LINK WITH NORMAL AGEING? by E. V. Plokhova, D. U. Akasheva, O. N. Tkacheva, I. D. Strazhesko, E. N. Dudinskaya, A. S. Kruglikova, M. V. Agaltsov, V. S. Pykhtina, N. V. Sharashkina, N. V. Brailova, D. A. Skvortsov, S. A. Boytsov

    Published 2015-04-01

    Aim. To study the age-related changes in structure of myocardium of the left ventricle and their relation with telomere length. With the age even in absence of cardiovascular diseases (CVD) and risk factors (CRF) there is a changing of the left ventricle (LV) myocardium structure. Probable mechanism...

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  3. 3
    INTERRELATION BETWEEN CARDIOVASCULAR RISK FACTORS AND TELOMERE BIOLOGY WITH THE SIGNS OF VASCULAR AGING

    INTERRELATION BETWEEN CARDIOVASCULAR RISK FACTORS AND TELOMERE BIOLOGY WITH THE SIGNS OF VASCULAR AGING by A. S. Kruglikova, I. D. Strajesko, O. N. Tkacheva, D. U. Akasheva, E. V. Plokhova, V. S. Pykhtina, E. V. Dudinskaya, O. Yu. Isaykina, N. V. Sharashkina, I. N. Ozerova, V. A. Vygodin, N. V. Gomyranova

    Published 2014-06-01

    Aim. To study interrelationship between cardiovascular risk factors and cellular and vascular aging processes. Material and methods. Totally 136 patients were included having no signs of cardiovascular diseases, diabetes 2nd type and receiving no drug therapy, but with one or several risk factors fo...

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  4. 4
    CORRELATIONS OF DIFFERENT STRUCTURAL AND FUNCTIONAL CHARACTERISTICS OF ARTERIAL WALL WITH TRADITIONAL CARDIOVASCULAR RISK FACTORS IN HEALTHY PEOPLE OF DIFFERENT AGE. PART 1

    CORRELATIONS OF DIFFERENT STRUCTURAL AND FUNCTIONAL CHARACTERISTICS OF ARTERIAL WALL WITH TRADITIONAL CARDIOVASCULAR RISK FACTORS IN HEALTHY PEOPLE OF DIFFERENT AGE. PART 1 by I. D. Strazhesko, O. N. Tkacheva, D. U. Akasheva, E. V. Dudinskaya, M. V. Agaltsov, A. S. Kruglikova, N. V. Brailova, V. S. Pykhtina, E. V. Plokhova, N. V. Sharashkina, O. Yu. Isaykina, V. A. Vygodin, S. A. Boytsov

    Published 2016-05-01

    Arterial wall status is determined by several characteristics, the main of them are as follows: pulse wave velocity (PWV), carotid arteries intima-media thickness (IMT), the presence of atherosclerotic plaques, endothelium-dependent vasodilation (EDVD). When these parameters change, the risk for car...

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  5. 5
    CORRELATIONS OF DIFFERENT STRUCTURAL AND FUNCTIONAL CHARACTERISTICS OF ARTERIAL WALL WITH TRADITIONAL CARDIOVASCULAR RISK FACTORS IN HEALTHY PEOPLE OF DIFFERENT AGE. PART 2

    CORRELATIONS OF DIFFERENT STRUCTURAL AND FUNCTIONAL CHARACTERISTICS OF ARTERIAL WALL WITH TRADITIONAL CARDIOVASCULAR RISK FACTORS IN HEALTHY PEOPLE OF DIFFERENT AGE. PART 2 by I. D. Strazhesko, O. N. Tkacheva, D. U. Akasheva, E. V. Dudinskaya, M. V. Agaltsov, A. S. Kruglikova, N. V. Brailova, V. S. Pykhtina, E. V. Plokhova, N. V. Sharashkina, O. Yu. Isaykina, V. A. Vygodin, S. A. Boytsov

    Published 2016-06-01

    Detection of principal subclinical arterial wall lesions is one of the most important aspects of effective cardiovascular disease (CVD) primary prevention. Such lesions include: arterial wall thickening, increased rigidity, endothelial dysfunction development. However, the role of traditional CVD ri...

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  6. 6
    INTERRELATION OF METABOLIC SYNDROME COMPONENTS WITH CELL AND VESSEL AGING PARAMETERS

    INTERRELATION OF METABOLIC SYNDROME COMPONENTS WITH CELL AND VESSEL AGING PARAMETERS by I. D. Strajesko, O. N. Tkacheva, D. U. Akasheva, E. V. Dudinskaya, M. V. Agaltsov, A. S. Kruglikova, N. V. Brailova, V. S. Pykhtina, E. V. Plokhova, O. Yu. Isaykina, V. A. Vygodin, N. V. Gomyranova, S. A. Boytsov

    Published 2014-06-01

    Aim. To study the interrelation of different MS components and parameters of cell and vessel aging.Material and methods. Totally 136 patients studied with the age 25-75 y. without any signs of CVD or other chronic diseases, not receiving any continuous drug therapy. In all patients the antropometric...

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  7. 7
    RELATION OF CARDIOVASCULAR RISK FACTORS AND LEUKOCYTE TELOMERE LENGTH

    RELATION OF CARDIOVASCULAR RISK FACTORS AND LEUKOCYTE TELOMERE LENGTH by I. D. Strajesko, I. N. Tkacheva, D. U. Akasheva, E. V. Dudinskaya, M. V. Agaltsov, A. S. Kruglikova, N. V. Brailova, V. S. Pykhtina, E. V. Plokhova, I. N. Ozerova, M. S. Pokrovskaya, V. A. Vygodin, D. A. Skvortsov, S. A. Boytsov

    Published 2016-06-01

    Telomere length (TL) is a recognized marker of replicative cellular ageing, and related to the ageing of cardiovascular system with the risk of cardiovascular diseases development (CVD). Chronic inflammation and oxidative stress significantly determine the velocity of telomeres shortening, and most...

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