Résultats de la recherche - V. Blinov

Generality of neurobiological processes in the most common CNS disorders could be verified. Thus, the acute pathology of the nervous system is accompanied by increased permeability ("breakthrough") of blood-brain barrier (BBB), which is trigger for inclusion of autoimmune mechanisms. This...

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There is a non-diminishing interest in the assessment of the blood-brain barrier (BBB) resistance and prediction of the severity and outcomes of the perinatal hypoxic-ischemic lesion of the CNS using the analysis of concentration of neuron-specific proteins in biological fluids. This defines the obj...

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Perinatal hypoxic-ischemic damage of the CNS is a major cause of mortality and neonatal incapacitating. The severity and prognosis is not always possible to accurately determine by clinical and tools methods of examination. Neurospecific proteins (NSP) could be as markers of pathological processes....

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Preeclampsia (gestosis) and eclampsia, as well as the acute intranatal hypoxy often act as trigger for the development of the perinatal hypoxic-ischemic brain injury. That is accompanied by such typical structural changes as periventricular leukomalacia (PVL) and intraventricular hemorrhages (IVH)....

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becoming increasingly widespread evaluation of the blood-brain barrier (BBB) resistance to predict severity and outcome of epilepsy, stroke, traumatic brain injury (TBI) and other neurological disorders by assessment of neuron-specific proteins (NSP)  concentration in biological fluids. In this work...

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CNS hypoxic-ischemic lesion is one of the causes of newborns invalidism in perinatal period. Under the «perinatal hypoxia» the complex of symptoms caused by oxygen insufficiency of fetus and newborn is considered. Combined prenatal and early neonatal impact of hypoxia is considered as a perinatal hy...

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Introduction. Non-alcoholic fatty liver disease (NAFLD) is increasingly recognized as an important and common public health problem that can lead to cirrhosis and hepatic failure (hepatocellular carcinoma – HCC). It may be the most prevalent liver disease. However knowledge of the epidemiology is li...

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The material provides a brief overview of authors composition (geography, affiliations) and distribution channels for “Epilepsy and Paroxysmal Conditions” journal content. Information on the number of published studies and relevant temporal citation pattern is provided. The journal is characterized...

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Perinatal hypoxic-ischemic encephalopathy (HIE) is a one of common cause of damage to neonatal CNS. Electroencephalography (EEG) has diagnostic value for choice of therapeutic interventions and predicting of outcomes. Sarnat classification is used EEG findings. EEG-monitoring and amplitude-integrate...

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Investigation of dynamics of serum glial fibrillary acid protein (GFAP) concentration within the first 6 months of life of neonates with cerebral ischemia has both scientific and practical implications. Materials and methods. 49 neonates with perinatal hypoxic-ischemic lesion of the CNS and gestatio...

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Until recently, no classification of epileptic syndromes officially approved by the International League Against Epilepsy (ILAE) was available. In 2022, owing to many year-persistent efforts made by experts and the public community, the studies providing the definition and classification of epilepti...

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Abstract: altered permeability of the blood-brain  barrier (BBB) plays a key role in the pathogenesis of epilepsy as well as vascular, demyelinating, neurodegenerative central neural system (CNS) diseases, head injury, hypoxic-ischemic CNS damage in obstetric practice, and other common disorders.  T...

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Abstract: A number of pathophysiologic manifestations can be distinguished that are characteristic of both epilepsy and other common vascular, demyelinating and degenerative central neural system (CNS) diseases. This is a consequence of neural system's endogenizing capacity that determines the...

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Abstract: the current concept of the structural and functional organization of the blood-brain barrier (BBB) was discussed in part one of the literature review. In the second part, we describe the development of the BBB concept. Beginning from the twentieth of the last century, the process of accumu...

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Perinatal brain ingury including hypoxic-ischemic encephalopathy (HIE) is serious problem of healthcare. Data on HIE prevalence in Russia is quite heterogeneous. Generally, prevalence in Russia is higher than in developed countries. The article presents the existing data on the prevalence of HIE in...

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In current specialized literature for doctors today there is a lack of data on the incidence of neurological morbuduty in a hospital environment. The attempt to fill this gap of information for assessing the incidence was conducted based on data from medical records, patients referred for assessment...

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The Founder and Publisher became aware of a potential apparent conflict of interest – it is assumed that it is not entirely correct to continue to be the Editor-in-Chief at the “Epilepsy and Paroxysmal Conditions” Journal, being a member of the founders of an organization that has registered another...

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It is now known that coals throughout the world contain many valuable elements. In the Irkutsk Region, coal mining is provided by the resources of the Irkutsk coal-bearing basin. The Irkutsk basin is a large area of the Jurassic continental sedimentary deposits in the south of the Siberian craton, w...

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Currently, the number of judicial proceedings on real and alleged offenses and disputes in area of provision of medical care has been exponentially increased. Some of such proceedings become publicly disclosed, but many more of them remain unnoted in mass media and civilian society as a whole. Incre...

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Chronic liver diseases are a serious problem and a common cause of suffering and death in all countries. Non-alcoholic fatty liver disease (NAFLD) is a major cause of chronic liver diseases. Alcoholic liver disease (ALD) is a disease that occurs in the case of the long-term alcohol consumption. ALD...

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