Search Results - V. A. Belyavskaya
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Correlations between Humoral Immunity, Vaccination Period and Demographic Characteristics of First Immunized Smallpox Vaccine Recipients
Published 2020-03-01Get full textRelevance. After vaccination against smallpox is completed, more than 50% of the population are not immune to pathogens of the genus Orthopoxvirus, which creates the risk of mass infection if the smallpox virus is used as a biological weapon.Aim. To assess the correlations between humoral immunity,...
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Microbiome, immune system and cancer: three sides of the one medal
Published 2023-01-01Get full textPurpose of the study to analyze current ideas about the relationship between the microbiota (microbiome) and the human body in the aspect of cancer pathogenesis, ambivalent character of these interactions, and the role of the immune system and immunoinfammatory status that promotes carcinogenesis or...
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Endogenous and exogenous risk factors affecting the incidence of breast cancer in the population of Yakutia
Published 2023-06-01Get full textThe purpose of the study: to analyze the breast cancer incidence and breast cancer risk factors for the population of the Republic of Sakha (Yakutia) in 2011-2020. Material and Methods. The incidence of breast cancer in the population of Yakutia was analyzed using the data collected from population-...
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ASSOCIATION BETWEEN POLYMORPHISMS IN GENES ENCODING 2′-5′-OLIGOADENYLATE SYNTHETASES AND THE HUMORAL IMMUNE RESPONSE UPON VACCINATION AGAINST TICK-BORNE ENCEPHALITIS
Published 2018-07-01Get full textVaccination forms active immunity and represents an effective way of preventing tick-borne encephalitis (TBE). However, excessive vaccination is unjustified in terms of economics and medical ethics. One of the individualized approaches to vaccines is the selection of vaccine doses depending on the e...
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Probiotics against pathogenic bacteria and cancer
Published 2025-03-01Get full textThis review focuses on the role of probiotics as alternative prevention and treatment of cancer. In this regard, we discuss the alternative cancer biotherapeutic drugs including live or dead probiotics and their metabolites, such as short chain fatty acids, inhibitory compounds of protein, polysacch...
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Association between leukocyte telomere length and specific antibody levels after vaccination against tick-borne encephalitis
Published 2020-01-01Get full textThe primary objective of personalized vaccination is to induce an efficient immune defense while avoiding excessive immunization. Hence, it necessitates the development of methods for predicting the magnitude of the immune response prior to vaccination. Telomere length can be considered as a promisi...
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Value of constitutional polymorphisms gene <i>р53</i> at patients with non-Hodgkin’s lymphomas
Published 2008-12-01Get full text.
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Variability of the mitochondrial genome in young Yakut patients with breast cancer
Published 2024-01-01Get full textBackground. The Sakha (Yakutia) population, the indigenous population of Siberia living in Yakutia, has one of the lowest rates of breast cancer (BC) incidence worldwide. The low BC incidence among the indigenous population of Yakutia has been reported by several authors, but to date the reasons for...
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New mutation of the TP53 gene associated with the hereditary breast cancer in a young Tuvinian woman
Published 2022-01-01Get full textBackground. The identification of the ethnospecific mutations associated with hereditary breast cancer remains challenging. Next generation sequencing (Ngs) technology fully enables the compilation of germline variants associated with the risk for inherited diseases. Despite the success of the Ngs,...
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DNA PANEL DESIGN FOR GENOMIC STUDIES IN RUSSIAN CATTLE BREEDS
Published 2015-01-01Get full textA panel of 96 DNA samples that reflects the breadth of genetic diversity in popular Russian cattle breeds has been designed. The panel of cattle DNA contains 11 dairy breeds and 6 beef and beef-dairy breeds. The numbers of animals in each breed group vary from 4 to 8. The main criterion for selectio...
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Analysis of Vaccinal Process Peculiarities in Persons Immunized with Smallpox Live Vaccine in Case of Primary Vaccination and Revaccination
Published 2015-03-01Get full textImmunization against smallpox may be attended by serious complications. The premises for the differences in postvaccinal reaction intensity are underexplored. In this paper presented is the review of peculiarities of postvaccinal manifestations in members of the Russian population primarily immunize...
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A novel germline mutation of the <i>PALB2</i> gene in a young Yakut breast cancer woman
Published 2022-09-01Get full textBackground. Breast cancer (BC) is the most common female malignancy worldwide. Partner And Localizer of BRCA2 gene (PALB2) is directly involved in DNA damage response. Germline mutation in PALB2 has been identified in breast cancer and familial pancreatic cancer cases, accounting for approximately 1...
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