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    Phenotypic screening in influenza-infected zebrafish identifies Nrf2-mediated compound protective against ischemia-reperfusion injury

    Phenotypic screening in influenza-infected zebrafish identifies Nrf2-mediated compound protective against ischemia-reperfusion injury by Elyse Latreille, Avinash Naraiah Mukkala, Rajiv Sanwal, Junghwa Yun, Kuiru Wei, Raluca Petrut, Nikki Zamani Farahani, Tristan Philip, Leo Xu, Tom Bateman, Chuxi Pan, David E. Williams, Trevor Moraes, Xiao-Yan Wen, Ori Rotstein, Raymond J. Andersen, Warren L. Lee

    Published 2025-08-01

    Summary: Excessive inflammation contributes to tissue injury in conditions including acute respiratory distress syndrome and ischemia-reperfusion. Moderation of inflammation is a potential therapeutic approach. A phenotypic screen of chemical libraries in influenza A-infected zebrafish identified ae...

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