Search Results - Tong LU
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Fuzzy multicriteria decision-making for assessing multinational enterprises’ outbound investment destinations on the basis of tax factors
Published 2025-07-01Get full textTaxes are a crucial consideration in a multinational enterprise’s (MNE)’s choice of overseas market to invest in. Taxes are affected by a variety of factors, and these factors are prioritized vis-à-vis each other in such investment decision-making. The present study thus developed a framework for e...
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Global Hotspots of Whale–Ship Collision Risk: A Multi-Species Framework Integrating Critical Habitat Zonation and Shipping Pressure for Conservation Prioritization
Published 2025-07-01Get full textThe expansion of global maritime activities threatens marine ecosystems and biodiversity. Collisions between ships and marine megafauna profoundly impact vulnerable species such as whales, who serve as keystone predators. However, the specific regions most heavily affected by shipping traffic and th...
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Comparative Metagenomics Reveals Microbial Diversity and Biogeochemical Drivers in Deep-Sea Sediments of the Marcus-Wake and Magellan Seamounts
Published 2025-06-01Get full textSeamounts are distributed globally across the oceans and are generally considered oases of biomass abundance as well as hotspots of species richness. Diverse microbial communities are essential for biogeochemical cycling, yet their functional partitioning among seamounts with geographic features rem...
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Endosialin promotes vascular maturation by inhibiting Cyr61 expression in melanoma metastasis
Published 2025-07-01Get full textBackgroundExtensive tumor cell metastasis is associated with poor patient prognosis. Tumor endothelial cells demonstrate distinct proangiogenic phenotypes compared to normal endothelial cells, partially mediated by pericyte-derived secreted factors. Endosialin, a pericyte biomarker implicated in vas...
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A comprehensive analysis of the tryptophan metabolism-related gene signature to predict the prognosis of esophageal squamous cell carcinoma based on multi-omics
Published 2025-08-01Get full textBackgroundTryptophan (Trp) metabolism plays a vital role in tumor development and outcomes. However, Trp in esophageal squamous cell carcinoma (ESCC) remains poorly understood. We aimed to explore the role and mechanism of Trp metabolism in ESCC.MethodsWe integrated single-cell RNA (scRNA) sequencin...
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Systems biology approaches investigating mitochondrial dysfunction in cyanotic heart disease: a systematic reviewResearch in context
Published 2025-08-01Get full textSummary: Background: Cyanotic congenital heart disease (CCHD) affects over 3 million individuals globally and can progress to heart failure. Mitochondrial dysfunction is well established in adult heart failure and is also a central feature of CCHD. CCHD cyanosis itself contributes to further mitoch...
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Protective efficacy of an H5/H7 trivalent inactivated vaccine produced from Re-11, Re-12, and H7-Re2 strains against challenge with different H5 and H7 viruses in chickens
Published 2020-09-01Get full textWe developed an H5/H7 trivalent inactivated vaccine by using Re-11, Re-12, and H7-Re2 vaccine seed viruses, which were generated by reverse genetics and derived their HA genes from A/duck/Guizhou/S4184/2017(H5N6) (DK/GZ/S4184/17) (a clade 2.3.4.4d virus), A/chicken/Liaoning/SD007/2017(H5N1) (CK/LN/S...
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