Search Results - Tingting Zhang

Study region: Temperate water-limited regions in northern China. Study focus: While restoring vegetation in China’s temperate water-limited regions is crucial for combating desertification, its hydrological effects—whether causing soil moisture (SM) drying or wetting—remain a topic of debate. This s...

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Neurological disorders (e.g., Alzheimer’s disease, Parkinson’s disease, and stroke) have complex pathogenesis and affect a substantial proportion of the population; yet, available treatments have poor or limited efficacy, and the patients have a poor prognosis, with high morbidity and mortality. Dih...

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The increasing frequency of extreme events presents significant challenges to the security and reliability of electric-hydrogen energy systems, where traditional optimal sizing methods often fail to address supply–demand imbalance risks under typical conditions. To bridge this gap, in the present st...

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Blueberry growth is closely tied to its rhizosphere’s microbial communities. Recent advancements in high-throughput sequencing and multi-omics technologies have enhanced the investigation of variations in rhizosphere microbial communities and their functional roles across different plant cultivars....

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IntroductionThis study investigates the effect of shapes in food packaging graphics (SFPG) on consumer purchase intentions. While prior research has primarily focused on cross-modal associations between SFPG and other sensory modalities (e.g., taste, smell), the direct influence of SFPG on purchase...

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<i>Salmonella enterica</i> serovar Typhimurium (<i>S.</i> Typhimurium) is an intracellular pathogen that survives and replicates within host cells. Macrophages, key immune cells in infection defense, play a vital role in pathogen clearance through polarization (M1/M2) and NLR...

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This study investigated the accumulation characteristics and associated health risks of 11 trace elements (Al, Rb, Cr, Ni, Mo, Sr, Pb, Ba, Ag, As, and Ga) in four crucian carp varieties: gene-edited intermuscular bone-free crucian carp (<i>Carassius auratus,</i> WUCI) and its sibling wil...

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To address the challenges of nonspecific adsorption interference and low mass transfer efficiency encountered by electrochemiluminescence (ECL) sensors in complex biological matrices, this study developed a Mn@CeO₂ nanozyme-based sensing interface. The Mn-doped CeO<sub>2...

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BackgroundNucleosome assembly protein 1-like 5 (NAP1L5), a critical regulator of gene transcription and nucleosome assembly, has been implicated in the progression and poor prognosis of various cancers. However, its specific role and molecular mechanisms in acute myeloid leukemia (AML) remain largel...

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γ-aminobutyric acid (GABA) is a four-carbon non-protein amino acid, with many regulatory effects in humans. It aids in regulating blood glucose levels and pressure and is widely recognized for its ability to promote cognitive balance through the alleviation of stress and improvements in sleep qualit...

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Shikonin, a botanical drug extracted from Lithospermum erythrorhizon, exhibits anti-cancer effects in various cancer cell lines. However, the mechanisms underlying these effects have not been completely elucidated yet. Here, we showed that Shikonin induces apoptosis and autophagy in A375 cells and i...

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Alantolactone (Ala), a major sesquiterpene lactone extracted from Inula helenium, exerts potent anti-tumour activities in various cancers. However, the underlying mechanism of such activities is still ambiguous. This study focused on evaluating the anti-tumour effects and molecular mechanisms of Ala...

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Podophyllotoxin (PPT), an aryltetralin-type lignan isolated from Podophyllum species, exhibits a wide range of biologic and pharmacologic activities, and mainly serves as an antiviral agent or antitumor drug in clinical applications. However, the therapeutic potential of PPT has been hindered due...

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The desert locust (<i>Schistocerca gregaria</i>) represents one of the most destructive agricultural pests globally, renowned for its ability to form massive swarms that can devastate crops and threaten food security across vast regions. Despite the widespread application of the CRISPR/C...

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Abstract Efficient delivery of biomolecules into neurons has significant impacts on therapeutic applications in the central nervous system (CNS) and fundamental neuroscience research. Existing viral and non‐viral delivery methods often suffer from inefficient intracellular access due to the endocyti...

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IntroductionThe incidence of platelet transfusion refractoriness (PTR) and its impact on survival outcomes in patients with severe aplastic anemia (SAA) undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains unclear.MethodsWe investigated the incidence of early PTR (within...

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