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  1. 1

    Construction of Green Villages/Townships Evaluation Model for Economic Metropolitan Circle by Deyong Zhang, Tian Tian

    Published 2025-06-01

    In recent years, the Chinese government has proposed the concept of ‘green villages/townships’, but the lack of implementation standards is hindering the achievement of this goal. The Northern Zhejiang region was selected as a case study to address this issue. The region’s overall traits were examin...

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  2. 2

    CLEAR: Cross-Document Link-Enhanced Attention for Relation Extraction with Relation-Aware Context Filtering by Yihan She, Tian Tian, Junchi Zhang

    Published 2025-07-01

    Cross-document relation extraction (CodRE) aims to predict the semantic relationships between target entities located in different documents, a critical capability for comprehensive knowledge graph construction and multi-source intelligence analysis. Existing approaches primarily rely on bridge enti...

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  3. 3

    GCRV-II Triggers B and T Lymphocyte Apoptosis via Mitochondrial ROS Pathway by Jie Wang, Wen-Jing Dong, Chang-Song Wu, Tian-Tian Tian, Xu-Jie Zhang, Yong-An Zhang

    Published 2025-06-01

    Grass carp reovirus (GCRV), particularly the highly prevalent genotype II (GCRV-II), is known to infect peripheral blood leukocytes (PBLs) of grass carp. However, it is unclear whether GCRV-II can induce apoptosis in bystander lymphocytes within infected PBLs. Here, we have shown that GCRV-II infect...

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  4. 4

    Effects of nitrogen application rates and irrigation regimes on grain yield and water use efficiency of maize under alternate partial root-zone irrigation by Dong-liang QI, Tian-tian HU, Xue SONG

    Published 2020-11-01

    Faced with the scarcity of water resources and irrational fertilizer use, it is critical to supply plants with water and fertilizer in a coordinated pattern to improve yield with high water use efficiency (WUE). One such method, alternate partial root-zone irrigation (APRI), has been practiced world...

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  5. 5

    N-nitrosodimethylamine removal improvement: Effect of filtration parameters on coagulation enhanced sand and activated carbon filtration in micro-polluted raw water treatment by Olubunmi M. Olukowi, Tian Tian, Xie Yan, Zhang Yuejun

    Published 2025-07-01

    N-nitrosodimethylamine (NDMA) is a carcinogen nitrogenous disinfection by-product, recently shown to be removed by coagulation coupled with rapid-sand-filtration (RSF) and/or activated-carbon-filtration (ACF). In order to improve NDMA removal-rate, key filter design and operational parameters were s...

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  6. 6

    Ultra-Compact Mach–Zehnder Refractometer Based on Rice-Shaped Air Cavity Beam Expansion by Zonghao Mu, Tian Tian, Yiwei Ma, Song Li, Tao Geng

    Published 2025-06-01

    This paper reports and demonstrates, for the first time, a Mach–Zehnder interferometer (MZI) sensor for refractive index (RI) detection based on a rice-shaped air cavity (RAC). In this design, RACs are inserted on both sides of a no-core fiber (NCF), functioning as a beam expander and receiver. When...

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  7. 7
  8. 8

    Computational nanobody design through deep generative modeling and epitope landscape profiling by Liyun Huo, Tian Tian, Yanqin Xu, Qin Qin, Xinyi Jiang, Qiang Huang

    Published 2025-01-01

    Nanobodies, one-tenth the size of conventional antibodies, have gained attention as therapeutic agents for autoimmune diseases, cancer, and viral infections. However, traditional methods for nanobody discovery are often time-consuming and labor-intensive. In this study, we present a computational de...

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  9. 9

    MiR-638 suppresses the progression of oral squamous cell carcinoma through wnt/β-catenin pathway by targeting phospholipase D1 by Kai-Liang Tang, Han-Ying Tang, Yi- Du, Tian Tian, Shi-Jiang Xiong

    Published 2019-12-01

    Objective The current study aimed to explore the function of miR-638 on the progression of oral squamous cell carcinoma (OSCC) and relevant molecular mechanisms.Methods Expression profile of miR-638 in OSCC tissues and cells was detected using quantitative real-time polymerase chain reaction (qRT-PC...

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  10. 10
  11. 11

    Engineering thermotolerant microbial strains via TrRCC1 overexpression for efficient bioethanol production by Tingting Chen, Xiao He, Xinyan Zhang, Tian Tian, Jian Cheng, Tingting Long, Yonghao Li

    Published 2025-06-01

    Efficient conversion of corn stover to bioethanol via simultaneous saccharification and fermentation (SSF) is a promising strategy for sustainable biofuel production. A major current barrier to this process is the limited thermotolerance of Saccharomyces cerevisiae, which hampers its performance und...

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  12. 12

    Epidemiological characteristics of invasive meningococcal disease and carriage prevalence of Neisseria meningitidis in the Xinjiang Uygur Autonomous Region, China, 2004–2023: a ret... by Halimubieke Nazhaerbieke, Wenhui Fu, Zhaoguo Lan, Yesitai Muheiyati, Tian Tian, Caipilima Wuqierjiafu, Na Xie

    Published 2025-07-01

    Objective The Xinjiang Uygur Autonomous Region (Xinjiang) currently exhibits the high incidence rates of invasive meningococcal disease (IMD) in China. Current epidemiological data on meningococcal carriage rates among asymptomatic individuals remain sparse, with limited population-based studies sys...

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  13. 13

    Single-cell spatial transcriptomics reveals pathogenic mechanism of renal fibrosis in imiquimod-induced lupus nephritis in mice by Yanan Xing, Yanru An, Tian Tian, Li Pu, Zhigang Lu, Ning Liang, Longqi Liu, Zhouchun Shang

    Published 2025-09-01

    A deeper understanding of the cellular and molecular pathology pathways of renal fibrosis in lupus nephritis (LN) is essential for the accurate disease assessment and the development of novel therapeutic strategies. In this study, we employed advanced spatial transcriptomics technique to elucidate t...

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  14. 14

    Proton Pump Inhibitors Do Not Reduce the Risk of Esophageal Adenocarcinoma in Patients with Barrett's Esophagus: A Systematic Review and Meta-Analysis. by Qiang Hu, Tian-Tian Sun, Jie Hong, Jing-Yuan Fang, Hua Xiong, Stephen J Meltzer

    Published 2017-01-01

    <h4>Objectives</h4>Proton pump inhibitors (PPIs) have been used for treatment of Barrett's esophagus (BE) for many years. However, the connection between PPIs and esophageal adenocarcinoma (EAC) in patients with BE has still been controversial. The current systematic review and meta...

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  15. 15

    A Dynamic Network Model for Forced Imbibition Considering Competition Between Main‐Meniscus Flow and Corner Flow by Wenbo Gong, Wenhai Lei, Tian Tian, Jiangtao Zheng, Yang Liu, Yuedi Wang, Yang Ju, Moran Wang

    Published 2025-07-01

    Abstract The pore‐scale interfacial dynamics including main‐meniscus flow and corner flow usually occurs in heterogeneous porous media and significantly affects the macroscopic multiphase flow process. Numerical research on the competition between main‐meniscus flow and corner flow remains challengi...

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  16. 16

    Effects of probucol on restenosis after percutaneous coronary intervention: a systematic review and meta-analysis. by Jichen Liu, Menghao Li, Hao Lu, Weiguang Qiao, Dan Xi, TianTian Luo, Haowei Xiong, Zhigang Guo

    Published 2015-01-01

    <h4>Background</h4>Restenosis after percutaneous coronary intervention (PCI) is a remained clinical problem which limits long-term success of PCI. Although there was recognition that probucol in treating restenosis after percutaneous transluminal coronary angioplasty, the efficacy of pro...

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  17. 17

    Study on cutting force in laser-assisted ultrasonic elliptical vibration machining (LUEVM) of high volume SiCp/Al composites by Peicheng Peng, Tian Tian, Heshuai Yu, Daohui Xiang, Ke Niu, Wei Gao, Yanqin Li, Zhaojie Yuan, Guofu Gao

    Published 2025-09-01

    Laser assisted machining (LAM) and ultrasonic elliptical vibration assisted machining (UEVAM) are effective in reducing cutting force and boost the cutting capability of SiCp/Al composite materials, compared to traditional machining (TM). However, the characteristics of high frequency intermittent c...

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  18. 18

    Expression and clinical significance of S100A8/9 in adults with secondary phagocytic lymphohistiocytosis by Ziwei Fang, Xin Gao, Limin Duan, Jujuan Wang, Tian Tian, Ji Xu, Yongqian Shu, Guangli Yin, Hongxia Qiu

    Published 2025-07-01

    IntroductionThe study aimed to investigate the diagnostic and prognostic value of serum S100A8/9 levels with sHLHa, a high-mortality multiorgan inflammatory syndrome with no reliable clinical biomarkers, where calreticulin’s role is unclear.MethodsThis was a study of 67 newly diagnosed sHLHa patient...

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  19. 19

    Overexpression of TuABCC4 is associated with abamectin resistance in Tetranychus urticae Koch by Mingmei Wu, Rui Dong, Yan Zhang, Haojie Liao, Tian Tian, Dandan Xu, Youjun Zhang, Zhaojiang Guo, Shaoli Wang

    Published 2025-06-01

    Pesticide resistance greatly limits control efficacy after the long-term application of pesticides. The two-spotted spider mite, Tetranychus urticae Koch, is a notorious agricultural pest worldwide that is resistant to various pesticides, including abamectin. While some studies of abamectin resistan...

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  20. 20

    Purification, Structural Characterization, and Immunomodulatory Activity of an Exopolysaccharide from <i>Acetilactobacillus jinshanensis</i> BJ01 in <i>Baijiu</i> Fermentation Grai... by Tian Tian, Bo Wan, Ying Xiong, Han Wang, Yuanyuan An, Ruijie Gao, Pulin Liu, Mingchun Zhang, Lihong Miao, Weifang Liao

    Published 2025-06-01

    This study aims to identify the chemical structure and immunomodulatory activity of exopolysaccharides (EPSs) from <i>Acetilactobacillus jinshanensis</i> BJ01 and suggest its potential applications in the pharmaceutical field and as functional food additives. The EPS-1 produced by <i&...

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