Search Results - Tian Chen
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Unveiling the Intricate Causal Nexus Between 91 Circulating Inflammatory Proteins and Perianal Abscess Through a Comprehensive Bidirectional Two‐Sample Mendelian Randomization Anal...
Published 2025-06-01Get full textABSTRACT Background The link between circulating inflammatory proteins and perianal abscess remains uncertain. This study utilized the Mendelian randomization approach to examine the potential causality of 91 circulating inflammatory proteins in relation to perianal abscess (PA) and assessed the bid...
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Ultrasound Improves Gallbladder Contraction Function: A Non-Invasive Experimental Validation Using Small Animals
Published 2025-06-01Get full textBackground: Gallbladder hypomotility is a key pathogenic factor in cholelithiasis. Non-invasive interventions to enhance gallbladder contractility remain limited. Ultrasound therapy has shown promise in various muscular disorders, but its effects on gallbladder function are unexplored. Methods: This...
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Identifying the Combined Impacts of Sensor Quantity and Location Distribution on Source Inversion Optimization
Published 2025-07-01Get full textSource inversion optimization using sensor observations is a key method for rapidly and accurately identifying unknown source parameters (source strength and location) in abrupt hazardous gas leaks. Sensor number and location distribution both play important roles in source inversion; however, their...
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TBK1 phagosomal recruitment enhances antifungal immunity via positive feedback regulation with SRC
Published 2025-07-01Get full textSummary: TANK-binding kinase 1 (TBK1) is a versatile serine/threonine protein kinase that is mainly recognized for its canonical role in antiviral immunity through interferon induction. Here, we report a previously uncharacterized function for TBK1 in antifungal defense. Using proteomic analysis, we...
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The research on the association between genetic alterations of DLBCLs and 18F-FDG PET/CT SUVmax and their clinical significance
Published 2025-06-01Get full textBackground and purpose: Next generation sequencing-identified genetic alterations of diffuse large B cell lymphoma (DLBCL) and baseline SUVmax detected by 18F-FDG PET/CT were correlated with patients’ prognosis. However, their relationship and the associations with R-CHOP response of DLBCL are still...
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