Sökresultat - Tao Cui
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Integrated bioinformatics and experimental validation identify ATF3 as a key gene in secondary brain damage after intracerebral hemorrhage.
Publicerad 2025-01-01Hämta fulltext<h4>Background</h4>Secondary brain injury following intracerebral hemorrhage (ICH) is a critical clinical challenge, yet the molecular mechanisms driving neuronal damage remain poorly understood. This study investigates the role of the transcription factor ATF3 and its downstream effecto...
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NDL-Net: A Hybrid Deep Learning Framework for Diagnosing Neonatal Respiratory Distress Syndrome From Chest X-Rays
Publicerad 2025-01-01Hämta fulltext<italic>Objective:</italic> Neonatal Respiratory Distress Syndrome (NRDS) poses a significant threat to newborn health, necessitating timely and accurate diagnosis. This study introduces NDL-Net, an innovative hybrid deep learning framework designed to diagnose NRDS from chest X-rays (CX...
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Effects of subsoiling depth, period interval and combined tillage practice on soil properties and yield in the Huang-Huai-Hai Plain, China
Publicerad 2020-06-01Hämta fulltextCompaction layers are widely distributed in the Huang-Huai-Hai Plain, China, which restrict root growth and reduce yields. The adoption of subsoiling has been recommended to disrupt compacted soil layers and create a reasonable soil structure for crop development. In this paper, the effects of subso...
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Modulating TRPV1 and TRPA1 channels: a viable strategy for treating asthma using Chinese herbal medicines
Publicerad 2025-07-01Hämta fulltextAsthma represents a significant global health challenge, imposing a substantial burden on society worldwide. Over the past decades, the development of asthma medications has significantly reduced asthma-related mortality. However, current pharmacological treatment regimens have not yet demonstrated...
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Targeted myostatin loss-of-function mutation increases type II muscle fibers in Meishan pigs
Publicerad 2022-01-01Hämta fulltextMyostatin (MSTN) is a negative regulator of skeletal muscle growth and development. The skeletal muscle in MSTN−/– mice is significantly hypertrophied, with muscle fiber type II increasing significantly while muscle fiber type I decreasing. However, it is still not clear how the skeletal muscle type...
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Muscle hypertrophy in transgenic mice due to over-expression of porcine myostatin mutated at its cleavage site
Publicerad 2016-11-01Hämta fulltextMyostatin, a member of the transforming growth factor beta (TGF-β) superfamily, is a dominant inhibitor that acts to limit skeletal muscle growth and development. In this study, we generated transgenic mice that express porcine myostatin containg mutations at its cleavage site (RSRR) to evaluate its...
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Trade-offs from a family perspective: considerations in choosing between omalizumab and complementary alternative medicine for pediatric severe asthma
Publicerad 2025-07-01Hämta fulltextThe management of pediatric severe asthma poses significant challenges for families. When faced with the choice between targeted biologics like omalizumab and widely used complementary alternative medicine (CAM), families navigate a complex decision-making process influenced by multiple factors. Thi...
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