Search Results - T. M. Taranenko
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Studying the Immunogenic Properties of Plague Microbe Capsule Antigen F1 Conjugated with Nanoparticles of Colloid Gold and Silver
Published 2008-04-01Get full textInfluence of nanoparticles of colloid gold (CG) and silver (CS) on immunobiological properties of antigens and possibility of their application as adjuvants for antibody formation stimulation were studied. It was shown that F1 capsule antigen of plague microbe conjugated with nanoparticles of CG and...
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THE INFLUENCE OF COLLOID SILVER NANO-PARTICLES UPON IMMUNOBIOLOGIC PROPERTIES OF PLAGUE MICROBE CAPSULAR ANTIGEN
Published 2012-09-01Get full textThis study shows that Yersinia pestis capsular antigen F1 conjugated to the CS nano-particles demonstrates apparent immunogenic effects. When injected to the test animals it was able to stimulate the production of specific antibodies under smaller antigenic load, it caused activation of the genetic...
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Comparative Study of Some Physical-Chemical and Immunochemical Properties of Plague Microbe Lipopolysaccharide Preparations Obtained with the Help of Different Techniques
Published 2012-06-01Get full text, and degraded polysaccharide (PS) are easily soluble in water and in 0,9 % NaCl solution. They are homogenous and characterized by an adequate degree of purity. Aside from that, it is demonstrated that potentially PS is the most productive molecule fragment of LPS for the construction of plague imm...
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Analysis of Stability of Plague Chemical Vaccine (F1+MSA) Antigenic Components in the Tests of Accelerated Ageing and Stress Conditions
Published 2009-02-01Get full textCarried out was comprehensive immunochemical and immunobiological analysis of plague microbe species-specific capsule F1 protein, and glycoproteid main somatic antigen (MSA) the latter being common in specificity in closely related plague and pseudotuberculosis agents. Both preparations isolated fro...
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Results of Modeling Experiments in Designing Immuno-Enzyme Test-System for the Detection of Antibodies to <I>Yersinia pestis</I> F1 (ELISA-Ab-F1...
Published 2013-03-01Get full textDesigned is immuno-enzyme test-system for the detection of antibodies to Yersinia pestis capsular antigen F1 – “ELISA-Ab-F1 Yersinia pestis”. On the model of laboratory mice it is demonstrated that this test-system is highly specific, its diagnostic titer being 1/320.Diagnostic va...
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