Search Results - T. Gamble
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What is the Minimum Risk that can be Estimated from an Epidemiology Study?
Published 2011Get full textNone
Electronic Book Chapter
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The role of systematic reviews in pharmacovigilance planning and Clinical Trials Authorisation application: example from the SLEEPS trial.
Published 2013-01-01Get full text<h4>Background</h4>Adequate sedation is crucial to the management of children requiring assisted ventilation on Paediatric Intensive Care Units (PICU). The evidence-base of randomised controlled trials (RCTs) in this area is small and a trial was planned to compare midazolam and clonidin...
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Application of T1 MRI in takotsubo cardiomyopathy
Published 2025-07-01Get full textIntroduction: Takotsubo cardiomyopathy is a temporary and severe left ventricular dysfunction caused by extreme emotional or physical stress, which confers significant mortality and morbidity.1 Cardiac magnetic resonance (CMR) sequences have been analysed to determine their diagnostic abilities in t...
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Concordance of Results from Randomized and Observational Analyses within the Same Study: A Re-Analysis of the Women's Health Initiative Limited-Access Dataset.
Published 2015-01-01Get full text<h4>Background</h4>Observational studies (OS) and randomized controlled trials (RCTs) often report discordant results. In the Women's Health Initiative Calcium and Vitamin D (WHI CaD) RCT, women were randomly assigned to CaD or placebo, but were permitted to use personal calcium and...
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Is there a "sweet spot" of model complexity for qualitative models used in Ecosystem-Based Management?
Published 2025-01-01Get full textEcosystem models have been developed to help support Ecosystem-Based Management and to help provide better management advice that can account for ecosystem impacts (e.g., climate, species interactions, fishing behaviour). Quantitative end-to-end models have proven to be very useful strategically for...
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Systematic review of the empirical evidence of study publication bias and outcome reporting bias - an updated review.
Published 2013-01-01Get full text<h4>Background</h4>The increased use of meta-analysis in systematic reviews of healthcare interventions has highlighted several types of bias that can arise during the completion of a randomised controlled trial. Study publication bias and outcome reporting bias have been recognised as a...
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Probe Sequencing Analysis of Regenerating Lizard Tails Indicates Crosstalk Among Osteoclasts, Epidermal Cells, and Fibroblasts
Published 2025-05-01Get full textLizards are distinguished as the only amniotes, and closest relatives of mammals, capable of multilineage epimorphic regeneration. Tail blastemas of green anole lizards (<i>Anolis carolinensis</i>) consist of <i>col3a1<sup>+</sup></i> fibroblastic connective tissu...
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Effectiveness of Choosing Wisely recommendations in reducing physiotherapists’ intentions to refer for imaging and use electrotherapy for low back pain: a randomised controlled exp...
Published 2025-06-01Get full textQuestion What is the effect of Choosing Wisely recommendations on physiotherapists’ intentions to refer for imaging and use electrotherapy for low back pain?Design Three-arm parallel-group online randomised controlled trial.Participants Physiotherapists who treat people with low back pain.Interventi...
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Is a History of Gestational Diabetes Associated With Long‐Term Mental Health?—Findings From the GEMS 5‐Year Follow Up Study
Published 2025-07-01Get full textABSTRACT Introduction Gestational diabetes mellitus (GDM) is associated with poor long‐term maternal metabolic health. However, there is limited evidence on the effect of GDM on later maternal mental health. We, therefore, aimed to compare mental health outcomes between women who had GDM and women w...
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Stepping into Who I Fully Am: A Creative Exploration of Autistic Menopause
Published 2025-05-01Get full textResearch suggests that perimenopause can compound existing struggles for some Autistic people, with potentially catastrophic consequences. Barriers to self-expression due to communication differences are also well-documented. Acknowledging this, our neurodiverse research team invited creative submis...
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Recruitment and retention strategies for improving representation in clinical research: A meta-synthesis.
Published 2025-01-01Get full text<h4>Objective</h4>To identify innovative strategies that may increase recruitment and/or retention of groups less represented in chronic disease clinical research.<h4>Methods</h4>A systematic review was conducted. Inclusion criteria were: (a) NIH-defined racial and ethnic min...
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Recruitment and retention strategies for improving representation in clinical research: A meta-synthesis
Published 2025-01-01 Get full text
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24. Comparing Predictors for Leadership in Surgical Subspecialty National Organizations
Published 2025-06-01 Get full text
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Evidence for the selective reporting of analyses and discrepancies in clinical trials: a systematic review of cohort studies of clinical trials.
Published 2014-06-01Get full text<h4>Background</h4>Most publications about selective reporting in clinical trials have focussed on outcomes. However, selective reporting of analyses for a given outcome may also affect the validity of findings. If analyses are selected on the basis of the results, reporting bias may occ...
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