Search Results - T. A. Lelyavina

Aim. To study trimetazidine (TZ) impact on the frequency of hospitalizations, structural and functional myocardium parameters, exercise tolerance (ET) in congestive heart failure patients (CHF) of nonischemic etiology (after myocarditis or DCMP), having complaints on chest pains.Material and methods...

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Aim. To assess the change in ergoreflex activity in heart failure patients with reduced left ventricular systolic function in the study of the effectiveness of physical training (PT) with original regimen, compared with PT with conventionally estimated regimen.Material and methods. Single-center ope...

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A distinction of the physical exertion into phases is necessary for on-time decisionmaking of the correct clinical decisions in medicine and for evaluation of the level ofsportsmen professional preparedness in sport medicine.Aim. 1) To reveal the consequence of compensatory reactions in human bodydu...

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To assess prognostic value of chronic heart failure (CHF) severity markers in patients aged over 74 years, and to optimise the risk stratification accordingly. This prospective study included 104 CHF patients aged 75 years or older, who were followed up for 2,5 years after hospital discharge. The ef...

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Aim. To assess the response of skeletal muscle and myocardium to original aerobic exercise (AE) program in patients with heart failure (HF) with reduced ejection fraction (HFrEF); to assess morphometric changes in skeletal muscle fiber after AE.Material and methods. The study included 100 patients w...

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The article presents a review of the literature on the current problem of modern transplantology – BK viral nephropathy after nephrotransplantation. Risk factors for BK virus reactivation in immunocompromised patients are reflected. The issues of screening and diagnosis of BK viral infection in peop...

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This paper reviews the sources and generality of knowledge regarding the adverse effects of immunosuppressive therapy, which play an important role in the full functioning of a transplant. The article regarding the importance of the dynamic impact of immunosuppressant medications on transplant funct...

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Three clinical cases of 2-year follow-up of young patients with chronic heart failure with a low left ventricular ejection fraction of non-coronarogenic genesis after implantation of the cardiac contractility modulation system are presented. Significant positive dynamics of clinical course and rever...

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Introduction. The gold standard of treatment for intermediate- and high-risk non-muscle-invasive bladder cancer (NMIBC) is transurethral resection of the bladder (TURB) in combination with intravesical therapy. However, this procedure may cause serious complications. At the same time, studies of var...

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The article highlights the central components of Russian heart failure (HF) management programs in actual clinical practice. The experience of the Competence Center of Almazov National Medical Research Center, as well as opportunities and prospects for improving the monitoring of decompensated HF.

Introduction. Atypical hemolytic uremic syndrome (aHUS) is a systemic orphan disease that reproduces as an uncontrolled activation of the alternative pathway of the complement system and is expressed as systemic thrombotic microangiopathy (TMA). The classical triad of aHUS symptoms are hemolytic ane...

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St. Petersburg, Russian Federation The paper presents a comparative assessment of different methods of treating symptomatic bladder outlet obstruction (BOO) in patients with benign prostatic hyperplasia (BPH) who underwent kidney transplantation (KT).

Aim. To determine whether the skeletal muscle of patients with chronic heart failure (CHF) retains the ability to regenerate and grow; to compare the effectiveness of long aerobic trainings, calculated by an individualized method, and conventionally calculated trainings (VO2peak values), in relation...

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Nephrolithiasis in a transplanted kidney is an important medical and social problem. The presence of renal calculi may not manifest clinically for a long time due to the peculiarities of the surgical intervention during organ transplantation. Development of chronic urinary tract infection and deteri...

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Aim: to estimate physical capacity and quality of life (QoL) and defi ne factors which impact on their dynamic in recipients after heart transplantation (HTx).Materials and methods. From January 2010 to September 2016 we performed 76 HTx (mean age – 45,4 ± 1,6 yrs). Physical activity (PA) was evalua...

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Aim. Heart failure (HF) is accompanied by skeletal muscle atrophy and exercise intolerance. The aim was to study the molecular mechanisms underlying the therapeutic effect of personalized exercise in patients with HF.Material and methods. RNA sequencing obtained from skeletal muscle biopsies before...

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Aim. To assess the 2-year prognosis of patients with heart failure with reduced ejection fraction (HFrEF) receiving cardiac contractility modulation (CCM).Material and methods. This single-center observational study included 55 patients (46 men, mean age 53±11 years) with NYHA class II-III HFrEF rec...

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Aim. To assess the clinical course and cardiac reverse remodeling in patients with heart failure (HF) with reduced ejection fraction (HFrEF) receiving cardiac contractility modulation (CCM) therapy.Material and methods. Fifty-five patients (mean age, 53±11 years, 46 males) with NYHA class II-III HFr...

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