Search Results - Svetlana G. Makarova

Food allergy is often the first manifestation of allergy in a child, and this problem is most relevant at an early age. With an allergic reaction to food, a seemingly not very significant pathology,  a so-called «atopic march» may begin with the development of  severe forms of allergic diseases in a...

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Height, body weight and body mass index are important parameters of health and are widely used in clinical practice, for assessing health of children, and for population studies. Amid the general globalization, the main trend of the present time is joining efforts of various countries for prevention...

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Providing the body with micronutrients — vitamins and minerals — is an indispensable component of human health and is essential in the  early stages of ontogenesis. However, studies conducted abroad and  in our country show that due to the fact that the content of  micronutrients in the daily ration...

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Congenital ichthyosis is a group (almost 100 clinical variants) of rare genetic skin diseases caused by pathogenic changes in more than 50 genes. Clinical features of ichthyosis, regardless of its genotype, are dry skin, peeling, hyperkeratosis frequently accompanied with erythroderma. These patient...

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Background. One of the key aspects in the development of atopic dermatitis (AtD) is epidermal barrier dysfunction leading to the penetration of pathogens and allergens through the skin with further body sensibilisation to them. Such pathological interaction can later on lead to the development of va...

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Intestinal microbiota is the factor that identifies considerably the human health. The impact of the microbial factor on a child begins long before his birth. Children have certain features in forming of immune response and intestinal microbiocenosis even before birth. Decline in diversity of intest...

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Background. Congenital ichthyoses (CIs) are a heterogeneous clinical-etiological group of genodermatoses. Typical clinical symptoms of this disease, regardless of the form, are generalized erythroderma, peeling, itching, hyperkeratosis, severe structural and functional disorders of the epidermal bar...

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In recent years, there has been a significant increase in the prevalence  of food allergies. Pathological conditions associated  with a food intolerance are becoming an increasingly urgent problem of pediatrics. According to different researchers, allergic lesions of the gastrointestinal tract occur...

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The article is devoted  to the issues  of introducing  complementary  foods  as prevention  of atopy  and diet therapy in children with food allergy. Food sensibilization,  as a rule, is the initial link of allergy manifestations.  It represents  the first step of the so-called atopic  march,  follo...

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Background. Children’s body weight is the predictor of pathologic elevation of arterial blood pressure (ABP) in adult life. The aim of the study is to divide the data on body weight and ABP in adolescents and to find correlations between them. Methods. The randomised study of 11 and 15 years old pup...

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Background. Children with congenital epidermolysis bullosa (CEB) can have vitamin D deficiency due to its malabsorption in intestine and reduced synthesis in skin as these patients have restrictions on staying in the sun. However, the prevalence of vitamin D insufficiency/deficiency among patients w...

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Background. Vitamins and minerals are significant components of the diet of a person of any age. Nowadays, when there is a focus on the ‘Western’ type of food, it is impossible to get the necessary amount of all vitamins and minerals with a normal diet, which explains the high prevalence of hypovita...

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Eosinophilic esophagitis is a chronic, immune/antigen-mediated esophageal inflammatory disease characterized by a pronounced eosinophilic infiltration of its mucous membrane. The occurrence of eosinophilia and damage of the esophageal mucous membrane is caused by exposure to food and aeroallergens,...

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Background. Congenital epidermolysis bullosa (CEB) belongs to the group of rare hereditary diseases with severe skin lesions. Congenital dystrophic epidermolysis bullosa (CDEB) is characterized by multiple organ dysfunction accompanied by impaired nutritional status. For a more accurate assessment o...

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Background. Dystrophic epidermolysis bullosa (EB) is a rare skin disease, and secondary osteoporosis is one of its complications. The bone remodeling condition in this pathology has not been studied enough. Objective. The aim of the study is to study the characteristics of phosphorus-calcium and bon...

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Neurogenetics is a thriving young science greatly contributing to the generally accepted concept of the brain development in health and disease. Thereby; scientists are not only able to highlight new key points in traditional ideas about the origin of diseases; but also to completely rethink their v...

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Background. Children of preschool and school age are at risk of developing vitamin deficiency. Screening of the vitamin provision of children remains an urgent problem of pediatrics. Objective. Our aim was to determine the prevalence of low excretion of watersoluble vitamins among healthy preschool...

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Background. Malformations in epidermal barrier in children with atopic dermatitis (AD) can cause transcutaneous sensitization with further development of allergic diseases that can worsen the AD course and significantly reduces patients’ quality of life.Objective. The aim of the study was to determi...

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Atopic dermatitis is a chronic multifactorial skin disease that is common enough in childhood. The article presents the current data on epidemiology and dynamics of incidence of pathological symptoms, pathogenesis basics, and key factors of the disease development, shows the current classification o...

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The article presents modern data on the epidemiology, etiology and clinical manifestations of food allergies in children. Evidence-based approaches to diagnosis, including differential, treatment, and prevention of food allergies in children are shown. Patient management tactics and algorithms are p...

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