Search Results - Su Liu
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Cloning, Tissue Distribution, and Transmembrane Orientation of the Olfactory Co-Receptor Orco from Two Important Lepidopteran Rice Pests, the Leaffolder (Cnaphalocrocis medinalis)...
Published 2013-10-01Get full textIn insects, the sense of smell is mainly mediated by olfactory receptors (Ors). Olfactory co-receptor (Orco), which is co-expressed with the Ors in almost all olfactory receptor neurons (ORNs), is demonstrated to be an essential component in the insect olfactory system. It can be potential target fo...
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Antioxidant action and potential neuroprotection of polyphenolics extracted from Astragalus membranaceus residue
Published 2025-07-01Get full textIntroductionPolyphenols, recognized as nutritional supplements, have emerged as promising therapeutic agents for various diseases, particularly brain disorders. However, due to the limitation of the extraction method, Astragalus membranaceus residues (AR) retain substantial bound phenolics with unex...
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Ibrutinib targets microRNA-21 in multiple myeloma cells by inhibiting NF-κB and STAT3
Published 2018-01-01Get full textThe oncogenic microRNA-21 contributes to the pathogenesis of multiple myeloma. Ibrutinib (also referred to as PCI-32765), an inhibitor of Bruton’s tyrosine kinase, while its effects on multiple myeloma have not been well described. Here, we show that microRNA-21 is an oncogenic marker closely linked...
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Intravenous Administration of sRNA Nanoparticles for Treatment of Osteoporosis in Mice
Published 2025-06-01Get full text<b>Background</b>: With the intensification of population aging, osteoporosis has become one of the significant public health issues affecting human health. Currently available medications for treating osteoporosis are associated with various adverse effects and resistance issues. Oligon...
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A novel immunocompetent transgenic mouse model of DHF reveals Syk-mediated Th2-polarized cytokine storm as a key driver of vascular leakage
Published 2025-12-01Get full textDengue virus (DENV) infection remains a critical global health threat, with DENV-2 being the most virulent serotype capable of causing lethal dengue hemorrhagic fever (DHF), a severe complication characterized by plasma leakage and hemorrhagic manifestations. While the search for viral receptors and...
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