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    Systematic identification and targeting of master regulator checkpoints (MRC) governing tumor microenvironment-mediated immune evasion

    Systematic identification and targeting of master regulator checkpoints (MRC) governing tumor microenvironment-mediated immune evasion by Pasquale Laise, Andrea Califano, Xiaoyun Sun, Gideon Bosker, Mariana Babor, Stuart Andrews, Lorenzo Tomassoni, Mariano Alvarez

    Published 2025-06-01

    Abrogating the immunoevasive role of the tumor immune microenvironment (TIME) represents a critical yet still elusive challenge in cancer treatment. Progress in this area has been hampered by both technological limitations and incomplete understanding of TIME-dependent immunoevasion mechanisms. We h...

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