Search Results - Sid O'Bryant

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  1. 1
    Low premorbid IQ may exacerbate the cognitive effects of apolipoprotein ε4 (APOE ε4): a multi-ethnic cross-sectional study from HABS-HD

    Low premorbid IQ may exacerbate the cognitive effects of apolipoprotein ε4 (APOE ε4): a multi-ethnic cross-sectional study from HABS-HD by Lubnaa Badriyyah Abdullah, Zhengyang Zhou, Ney Alex Alliey, Robert Barber, James Hall, Sid O’Bryant

    Published 2025-07-01

    IntroductionApolipoprotein allele 4 (APOE ε4) is associated with lower IQ scores during childhood and adolescence, but the influence of APOE ε4 and low IQ on late-life cognition is unknown. This study examines the association between APOE ε4 and cognitive outcomes based on premorbid intellectual abi...

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  2. 2
    Alzheimer's disease genetic risk: Top African American risk allele frequencies and genetic architecture among Mexican‐, African‐, and non‐Hispanic White Americans

    Alzheimer's disease genetic risk: Top African American risk allele frequencies and genetic architecture among Mexican‐, African‐, and non‐Hispanic White Americans by Mohammad Housini, Zhengyang Zhou, Lubnaa Abdullah, Gita Pathak, Reem Ayoub, John Gutierrez, Shea Andrews, Nicole Phillips, Sid O'Bryant, Robert Barber, For the HABS‐HD Study Team

    Published 2025-04-01

    Abstract INTRODUCTION Alzheimer's disease (AD) continues to be the sixth leading cause of death in the United States. Significant efforts are spent researching etiology and potential management strategies. Although minorities face a higher disease burden and are anticipated to make up 43% of th...

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  3. 3
    Psychosocial behavioral phenotypes of racially/ethnically minoritized older adults enrolled in HABS‐HD differ on neuroimaging measures of brain age gap, hippocampal volume, and cortical thickness

    Psychosocial behavioral phenotypes of racially/ethnically minoritized older adults enrolled in HABS‐HD differ on neuroimaging measures of brain age gap, hippocampal volume, and cor... by Alexandra L. Clark, Makenna B. McGill, Alexandra J. Weigand, Julie K. Wisch, Kalen Petersen, Beau Ances, Meredith N. Braskie, Sid O'Bryant, Kelsey R. Thomas, HABS‐HD Study Team

    Published 2025-04-01

    Abstract INTRODUCTION This study examined whether previously identified psychosocial behavioral phenotypes differed on structural neuroimaging markers. METHODS Latent profile analysis (LPA) employed in a sample of 1820 community‐dwelling older adults (1118 Hispanic and 702 Black) replicated previous...

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