Sökresultat - Shujun Zhang
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Development of a Starvation Response–Based Model and Its Application in Prognostic Assessment of Liver Hepatocellular Carcinoma av Xinjun Hu, Yafeng Liu, Shujun Zhang, Kaijie Liu, Xinyu Gu
Publicerad 2025-01-01Conclusion: In this study, we constructed the first risk model based on SRRGs to accurately predict the prognosis of LIHC, which provides a new idea for individualized treatment and targeted intervention.
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Purification and Inhibitor Screening of the Full-Length SARS-CoV-2 Nucleocapsid Protein av Chen Chen, Zhengfu Zhang, Qiao Zheng, Yingshun Zhou, Shujun Zhang
Publicerad 2025-06-01Severe acute respiratory syndrome coronavirus 2 has undergone several mutations since 2020, and novel variants continue to emerge to this day. The immune escape ability of the emerging mutants is enhanced and results in robust transmissibility. The neutralizing ability of the antibodies produced in...
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Identification of SMYD2 as a candidate diagnostic and prognostic biomarker for gastric cancer av Sichao Wang, Chuanxi Zhao, Dongmei Li, Qingzhi Liu, Cuiping Mao, Shanshan Ding, Shujun Zhang, Wenjing Shang
Publicerad 2025-07-01BackgroundHistone modification enzymes (HMEs) are associated with cancer development, treatment response, and prognosis. However, the potential roles of HMEs in gastric cancer (GC) remain unclear. This study aimed to investigate their biological functions and mechanisms in GC, with additional focus...
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Identification of the T-box transcription factor t-bet in chickens and its role in immune response av Yuxin Guo, Zhaocan Zhou, Hui Gao, Shujun Zhang, Zhi Chen, He Chang, Hong Cao, Li Gao, Yongqiang Wang, Shijun J. Zheng
Publicerad 2025-10-01T-bet (T-box transcription factor TBX21), encoded by the Tbx21 gene, is a key regulator of T helper 1 (Th1) cell differentiation and cellular immunity. However, the role of T-bet in avian species remains elusive. To investigate the role of T-bet in avian immune response, we cloned chicken T-bet (chT...
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Engineered small extracellular vesicles for targeted delivery of perlecan to stabilise the blood–spinal cord barrier after spinal cord injury av Wei Peng, Wentao Zhang, Wei Cui, Wenjin Chen, Yin Zhuang, Rupeng Chu, Jinghua Tan, Jingbo Xue, Yiguo Yan, Guoyong Yin, Shujun Zhang, Yong Xie
Publicerad 2025-06-01Abstract Background Destruction of the blood–spinal cord barrier (BSCB) following spinal cord injury (SCI) can result in various harmful cytokines, neutrophils, and macrophages infiltrating into the injured site, causing secondary damage. Growing evidence shows that M2 macrophages and their small ex...
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