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    Comprehensive fragmentation of cell-free repetitive DNA for enhanced cancer detection in plasma

    Comprehensive fragmentation of cell-free repetitive DNA for enhanced cancer detection in plasma door Mingguang Zhang, Shuohui Dong, Wei Rao, Shiwen Mei, Gang Hu, Ling Liu, Zhen Wang, Jianqiang Tang

    Gepubliceerd in 2025-07-01

    BackgroundRepetitive elements account for a large proportion of the human genome and undergo alterations during early tumorigenesis. However, the exclusive fragmentation pattern of DNA-derived cell-free repetitive elements (cfREs) remains unclear.MethodsThis study enrolled 32 healthy volunteers and...

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