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    The African swine fever virus p22 inhibits the JAK-STAT signaling pathway by promoting the TAX1BP1-mediated degradation of the type I interferon receptor

    The African swine fever virus p22 inhibits the JAK-STAT signaling pathway by promoting the TAX1BP1-mediated degradation of the type I interferon receptor by Haojie Ren, Yanjin Wang, Lian-Feng Li, Lan-Fang Shi, Yu-He Ma, Jun-Hao Fan, Xiao-Ya Pan, Han-Cheng Shao, Yuhang Zhang, Shichong Han, Bo Wan, Hua-Ji Qiu, Gai-Ping Zhang, Su Li, Wen-Rui He

    Published 2025-07-01 Get full text
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    The African swine fever virus p22 inhibits the JAK-STAT signaling pathway by promoting the TAX1BP1-mediated degradation of the type I interferon receptor.

    The African swine fever virus p22 inhibits the JAK-STAT signaling pathway by promoting the TAX1BP1-mediated degradation of the type I interferon receptor. by Haojie Ren, Yanjin Wang, Lian-Feng Li, Lan-Fang Shi, Yu-He Ma, Jun-Hao Fan, Xiao-Ya Pan, Han-Cheng Shao, Yuhang Zhang, Shichong Han, Bo Wan, Hua-Ji Qiu, Gai-Ping Zhang, Su Li, Wen-Rui He

    Published 2025-07-01

    African swine fever virus (ASFV) is the causative agent of African swine fever (ASF), a devastating disease epidemic in Asia and Europe. Large knowledge gaps regarding the biological characteristics of viral structural proteins have severely hindered the development of vaccines against ASF. The p22...

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