Search Results - Shengnan Han

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    Baicalein ameliorates DSS-induced ulcerative colitis in mice by inhibiting ferroptosis and regulating gut microbiota

    Baicalein ameliorates DSS-induced ulcerative colitis in mice by inhibiting ferroptosis and regulating gut microbiota by Weiguang Lv, Shengnan Han, Ke Li, Aimin Yan, Wei Wang, Wanping Lu, Jing Han, Chenggang Zhang

    Published 2025-07-01

    Ulcerative colitis (UC) is a nonspecific inflammatory disease. Baicalein has potential value in treating UC, but its mechanism is unclear. This study aims to evaluate the protective effects of baicalein on dextran sodium sulfate (DSS)-induced UC mice. The UC model was established by 4% DSS solution...

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    Baicalein from Scutellaria baicalensis mitigates oxidative stress through the IIS pathway in a C. elegans model of ulcerative colitis

    Baicalein from Scutellaria baicalensis mitigates oxidative stress through the IIS pathway in a C. elegans model of ulcerative colitis by Wei Wang, Xiaoyu Fu, Jianing Xu, Jianing Xu, Weiguang Lv, Shengnan Han, Yi Wang, Yu Xia, Jing Han, Ke Li, Chenggang Zhang

    Published 2025-06-01

    IntroductionUlcerative colitis (UC) is a chronic, nonspecific inflammatory bowel disease with limited therapeutic options. Baicalein, a phenolic flavonoid extracted from Scutellaria baicalensis, has been traditionally used in Chinese medicine for its potent anti-inflammatory, anti-tumor, and antivir...

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