Résultats de la recherche - Sai Zhu
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Design and Simulation of Optical Waveguide Digital Adjustable Delay Lines Based on Optical Switches and Archimedean Spiral Structures
Publié 2025-07-01Accéder au texte intégralIn the field of modern optical communication, radar signal processing and optical sensors, true time delay technology, as a key means of signal processing, can achieve the accurate control of the time delay of optical signals. This study presents a novel design that integrates a 2 × 2 Multi-Mode Int...
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ACSF2-PGK1 interaction promotes ferroptosis in renal tubular epithelial cells of diabetic nephropathy by regulating Keap1/Nrf2 signaling
Publié 2025-12-01Accéder au texte intégralObjectives Recent studies have highlighted the strong association between kidney disease and ferroptosis. However, the role of ferroptosis in diabetic nephropathy (DN) remains unclear. This study aimed to determine the role of ACSF2 in renal tubule injury in DN and its underlying mechanisms.Methods...
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A Dual Approach with Organoid and CRISPR Screening Reveals ERCC6 as a Determinant of Cisplatin Resistance in Osteosarcoma
Publié 2025-07-01Accéder au texte intégralAbstract Osteosarcoma (OS), the most prevalent primary bone malignancy in adolescents, is typically treated with cisplatin‐based chemotherapy. However, the development of cisplatin resistance often leads to relapse or metastasis, significantly impairing therapeutic efficacy. To tackle this issue, pa...
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