Suchergebnisse - Sai Zhu

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  1. 1
    Design and Simulation of Optical Waveguide Digital Adjustable Delay Lines Based on Optical Switches and Archimedean Spiral Structures

    Design and Simulation of Optical Waveguide Digital Adjustable Delay Lines Based on Optical Switches and Archimedean Spiral Structures von Ting An, Limin Liu, Guizhou Lv, Chunhui Han, Yafeng Meng, Sai Zhu, Yuandong Niu, Yunfeng Jiang

    Veröffentlicht 2025-07-01

    In the field of modern optical communication, radar signal processing and optical sensors, true time delay technology, as a key means of signal processing, can achieve the accurate control of the time delay of optical signals. This study presents a novel design that integrates a 2 × 2 Multi-Mode Int...

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  2. 2
    ACSF2-PGK1 interaction promotes ferroptosis in renal tubular epithelial cells of diabetic nephropathy by regulating Keap1/Nrf2 signaling

    ACSF2-PGK1 interaction promotes ferroptosis in renal tubular epithelial cells of diabetic nephropathy by regulating Keap1/Nrf2 signaling von Xinran Liu, Chaoyi Chen, Sai Zhu, Xiaomei Luo, Li Gao, Ziyun Hu, Yu Ma, Ling Jiang, Yonggui Wu

    Veröffentlicht 2025-12-01

    Objectives Recent studies have highlighted the strong association between kidney disease and ferroptosis. However, the role of ferroptosis in diabetic nephropathy (DN) remains unclear. This study aimed to determine the role of ACSF2 in renal tubule injury in DN and its underlying mechanisms.Methods...

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  3. 3
    A Dual Approach with Organoid and CRISPR Screening Reveals ERCC6 as a Determinant of Cisplatin Resistance in Osteosarcoma

    A Dual Approach with Organoid and CRISPR Screening Reveals ERCC6 as a Determinant of Cisplatin Resistance in Osteosarcoma von Ruiling Xu, Sai Zhu, Wenchao Zhang, Haodong Xu, Chao Tu, Honghui Wang, Lu Wang, Na He, Tang Liu, Xiaoning Guo, Xiaolei Ren, Zhihong Li

    Veröffentlicht 2025-07-01

    Abstract Osteosarcoma (OS), the most prevalent primary bone malignancy in adolescents, is typically treated with cisplatin‐based chemotherapy. However, the development of cisplatin resistance often leads to relapse or metastasis, significantly impairing therapeutic efficacy. To tackle this issue, pa...

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