Search Results - S. V. Saakyan

Thirty-six cases of metastatic dissemination were analyzed in detail in patients with uveal melanoma after treatment. The onset time and risk factors of metastatic spread after different treatment options for uveal melanoma are given.

Purpose: to assess the clinical course of metastatic orbital tumors (MOT) and the results of instrumental examination of patients. Material and methods. 50 MOT patients aged 5–84 years (ave. 56.9 ± 14.3), including 41 women (82 %) and 9 men (18 %), were examined for the clinical signs, the lateralit...

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Purpose: to describe a clinical case of ocular complications of gastric stromal tumor treatment with imatinib mesylate.Material  and methods. A patient aged 78 was examined  by general ophthalmologic and instrumental  methods,  including ultrasound  and spectral optical coherence tomography (SOCT).R...

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Purpose: to characterize the quality of life (QOL) of young patients with uveal melanoma (UM) after surgical treatment. Materials and methods. 23 patients with UM aged 11 to 25 (mean age 21±4,1 years, 11 females, 12 males) were surveyed on the issue. Of these, 17 people received eye-preserving treat...

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We analyze long-term changes of quality of life (QOL) in uvealmelanoma patients, depending on age and treatment type. The study involved 100 patients (28 males and 72 females) aged 11 to 79. The patients were divided in three age groups: group I (25 years or younger), II (26-59 years), III (over 60...

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A comprehensive examination was made in 93 patients, including 18 children, with tumors of the optic nerve (ON). Duplex ultrasound scanning was performed in 39 patients, of them there were 11 patients with ON gliomas and 28 with ON meningiomas. The specific computed tomographic and echographic signs...

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The study objective is to estimate the prevalence of different tumors of the visual organ among the adult population of the Nizhny Novgorod Region.Materials and methods. Epidemiological study was conducted on the basis of a retrospective analysis of medical documents of 1601 patients over 18 years o...

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Purpose. To reveal predictors of small choroidal melanoma transpupillary thermotherapy efficiency using optical coherence tomography-angiography.Patients and methods. 34 patients with small choroidal melanoma at an average age of 55.0 ± 2.9 years were examined. Optical coherence tomography-angiograp...

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Purpose. Evaluation of long-term results of uveal melanoma (UM) treatment in patients depending on clinical, hemodynamic and morphological parameters of the tumor.   Material and methods. Long-term results of treatment were analyzed in 394 UM patients aged 17 to 82 (mean age 53.1 ± 13.2). The median...

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Purpose: study of uveal melanoma (UM) cells receptor status to estrogen (ER) and progesterone (PR). Material and methods. 22 patients (8 men and 14 women) with UM aged 22 to 76 (mean 54.3 ± 2.2 years) were subjected enucleation (n = 20) or fine-needle aspiration biopsy, depending on clinical indicat...

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Purpose. Studying clinical and cytological signs of malignant epithelial genesis tumors of eye adnexa. Material and methods. In 2015–2020, 308 patients aged from 23 to 87 (58.0 ± 6.7) years with suspected malignant neoplasms of eyelid skin and conjunctiva were cytologically examined. The material fo...

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Purpose. To determine the possibilities of modern ultrasound methods in the detection of uveal melanoma (UM) extrascleral growth (EG).Patients and methods. The work is based on the results of the examination and treatment of 170 patients with UM who underwent enucleation, including 106 (62.5 %) wome...

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Purpose: To study the features of small choroidal melanoma and choroidal nevi angioarchitectonics using the optical coherence tomography angiography (OCTA).Patients and methods. We examined 128 patients with small choroidal neoplasms: 41 — with small choroidal melanoma (group 1), 42 — with suspiciou...

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We present a clinical case of untimely recognized and inadequately treated iris melanoma, which led to the development of secondary hypertension and secondary cataract in the absence of extrabulbar growth and the presence of bleb ossification during 6 months after trabeculectomy against the backgrou...

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Purpose. To analyze how the clinical and morphological features are associated with vital prognosis of iris melanoma patients.Material and methods. A retrospective analysis included 84 patients (54 women and 30 men) with iris melanoma treated between 2005 and 2019.The mean age at the time of treatme...

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Purpose. Using optical coherence tomography (OCT), determine the preclinical changes in optic nerve head (ONH) after chemotherapy in children with retinoblastoma (RB). Material and methods. 38 patients (76 eyes) were examined and treated: 15 girls, 23 boys with RB averagely aged 21.0 ± 1.5 months. O...

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Purpose: to analyze indications for enucleation in uveal melanoma (UM) patients after brachytherapy (BT). Material and methods. 52 patients with UM (31 females and 21 males) aged 25 to 74 years (mean age 53.2 ± 12.3) underwent an enucleation after a previously administered BT. Tumor sizes before BT...

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Purpose: to evaluate the effectiveness of transpupillary thermotherapy (TTT) of small calcified retinoblastomas (SR) having various calcification degrees. Material and methods. The results of treatment of 111 children (92 eyes, 198 tumors) with small calcified retinoblastomas by TTT were analyzed. A...

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To assess the role of multifocal electroretinography (mf-ERG) in preclinical diagnosis of tumor-associated distant maculopathy in small choroidal melanoma (CM) of extramacular localization.Material and methods. 35 patients (35 affected and 35 fellow eyes) with small CM of extramacular localization a...

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Purpose: to compare the regenerative activity of benign and malignant conjunctival tumors.Material and methods. The study was performed on 86 tumor biopsies from patients with a clinically diagnosed conjunctival neoplasm. Healthy tissues from the same eye were taken as a control sample. The optical...

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