Search Results - S. O. Lukyanova
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Association of TLR2 Arg753Gln gene polymorphism with its expression level in nonagenarians with frailty
Published 2024-07-01Get full textTLR2 is an exceptional pattern-recognizing receptor because of its ability to heterodimerise with different types of TLRs, which allows it to recognize a wide range of molecular structures on the surface of pathogens. Polymorphisms in genes involved in the TLRs signaling cascade may be a factor in h...
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Biomarkers of inflammaging in geriatric syndromes
Published 2025-06-01Get full textThe worldwide trend towards increasing life expectancy makes relevant the studies on aging and ageassociated pathology. The pathophysiologic mechanisms underlying geriatric syndromes remain insufficiently studied. It is hypothesized that chronic sterile inflammation (inflammaging) may be a key facto...
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Standardization of oral food challenges as a method for diagnosis of food allergy in children of the Russian Federation: study protocol and preliminary results
Published 2024-11-01Get full textBackground. Food allergy is a serious, life-threatening condition that negatively impacts the quality of life of patients and their families, especially among children. In Europe, approximately 7 million people suffer from food allergy, while in Russia, the prevalence varies from 5% to 30%. Accurate...
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