Search Results - S. K. Solovyev

The problem of increase of pension age in our country is discussed already from the first steps of market transformations of provision of pensions, i.e. quarter of the century, and without some visible advancement to its decision. At the same time all civilised countries have already developed the a...

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Article Retracted.A new stage of the pension reform in Russia scheduled for 2015 will be an extension of parametric and institutional reforms aimed at the restructuring of the economic and social system of the country to further adapt it to market conditions. The main areas of the reform are determi...

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The pension reform 2015 dramatically increased not only the public, but also academic interest to the problems of the national pension system. The discussions revealed serious discrepancies (often diametrically opposed) in the quantitative estimates of both the pension system and the economic and so...

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The whole armory of the drugs used in rheumatology is employed to treat systemic lupus erythematosus (SLE); how- ever, most of them have not got regulatory authorities' approval and are used off-label for SLE. The successful use of a biological agent rituximab (anti-CD20 monoclonal antibodies)...

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The paper details 15 new recommendations of the Canadian Rheumatology Association for the clinical monitoring of patients with systemic lupus erythematosus (SLE). During their development, the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) classification system for rating...

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A diversity of the clinical manifestations of systemic lupus erythematosus (SLE) and its undulating course with alternating remissions and exacerbations make this disease one of the most difficult ones to diagnose, treat, and evaluate the efficiency of therapy.Despite the fact that the recently deve...

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The problem of increase of pension age in our country is discussed already from the first steps of market transformations of provision of pensions, i. e. quarter of the century, and without some visible advancement to its decision. At the same time all civilised countries have already developed the...

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Systemic lupus erythematosus (SLE) is a prototype for chronic autoimmune disease. Its prevalence is 20 to 70 cases per 100,000 women and varies by race and ethnicity. Despite considerable progress in traditional therapy, many problems associated with the management of these patients need to be immed...

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Data on the clinical course and treatment of such as the severe disease systemic lupus erythematosus (SLE), are virtually lacking in Russia.Objective: to evaluate the clinical presentations of the disease and its treatment in adult patients with active SLE in the cities of three post-Soviet countrie...

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Objective: to provide a rationale for selecting a health-related quality of life (HRQOL) questionnaire in patients with systemic lupus erythematosus (SLE).Subjects and methods. The investigation enrolled 328 patients (298 women and 30 men) with documented SLE who met the 2012 Systemic Lupus Internat...

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The importance of comorbid infections in rheumatology has increased substantially in recent years, particularly in connection with the introduction of biological agents into clinical practice. One of the ways to solve this problem is to study and actively use vaccines. This review deals with the iss...

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Objective: To evaluate the efficacy of combination therapy with rituximab (RTM) and belimumab (BLM) in patients with systemic lupus erythematosus (SLE) during long-term follow-up.   Material and methods. Twelve patients with definite high- and moderate activity SLE were included in the study. Nine o...

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Objective: to investigate the effect of various biological agents (BAs), including combined treatment with rituximab (RTM) and belimumab (BLM), on the activity of systemic lupus erythematosus (SLE) and to evaluate their efficacy and impact on some parameters of humoral immunity.Subjects and methods....

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Objective: to assess changes in health-related quality of life (HRQoL) in patients with systemic lupus erythematosus (SLE) during performed therapy.Subjects and methods. The investigation included 128 patients with reliable SLE who fulfilled the 2012 SLICC criteria. Sixty-eight patients received sta...

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The paper presents an analytical literature review of the use of rituximab (RTM) in patients with systemic lupus erythematosus (SLE). It considers current views on the mechanisms of action of RTM, its efficacy in different organ damages in patients with SLE, particularly in those with lupus nephriti...

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Objective: To evaluate the impact of rituximab (RTM) therapy on the clinical, morphological, and immunological parameters of lupus nephritis (LN) activity. Subjects and methods. The study included 19 patients with types III and IV LN (WHO classification) with its 6-133-month history. Their mean age...

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The efficiency of glucocorticoid (GC) therapy for systemic lupus erythematosus (SLE) is beyond question and is confirmed by the experience gained over many decades of their use. However, there are many problems with prolonged GC use, even in its low and medium doses. In particular, the development o...

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