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Nuclear p62/SQSTM1 facilitates ubiquitin-independent proteasomal degradation of BMAL1. by Chenliang Zhang, Quanyou Wu, Huan Zhang, Ruichen Liu, Liping Li
Published 2025-07-01Brain and muscle arnt-like protein 1(BMAL1) is a critical regulator of circadian rhythm. Although transcriptional regulation of BMAL1 has been extensively studied, the mechanisms governing the stability of BMAL1 at the protein level remain unclear. p62/SQSTM1 is a crucial factor in proteostasis regu...
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