Search Results - Rui Yu
-
1
-
2
Comparative evaluation of three anti-dsDNA antibody detection methods in systemic lupus erythematosus: insights from a large monocentric cohort
Published 2025-04-01Get full textBackgroundAnti-double-stranded DNA (anti-dsDNA) antibodies at abnormal titer are of considerable diagnostic value for systemic lupus erythematosus (SLE). Current assays detecting anti-dsDNA antibodies show divergent properties, emphasizing the importance of selecting suitable assays. This study aims...
Article -
3
Water-mediated Mg2SiO4 layer microstructure evolution: A critical pathway to superior magnetic performance in grain-oriented electrical steel
Published 2025-07-01Get full textGrain-oriented electrical steel (GOES) is widely used as the core component of transformers. Mg2SiO4 (forsterite) layer formed by the reaction between magnesia separator coating and oxide layer on the surface of GOES plays important roles for the excellent magnetic performance of GOES. This study pr...
Article -
4
Multifunctional investigation of “drug–excipient unification” of natural polysaccharide nanocarriers: A new paradigm from drug delivery to adjuvant therapy
Published 2025-09-01Get full textThe concept of “drug–excipient unification” involves replacing or reducing traditional excipients with components that possess pharmacological activity, thereby simultaneously enhancing therapeutic efficacy and reducing toxicity. This concept can be effectively implemented in pharmaceutical formulat...
Article -
5
Artifact Removal in Long-Range Single Photon LiDAR via Waveforms-Guided Depth Image Estimation
Published 2024-01-01Get full textSingle-photon light detection and ranging (LiDAR) has widespread applications due to the ultra-high sensitivity of the single-photon detector. However, the reconstruction has been plagued by multiple types of noise caused by crosstalk, dark counts, and background light. Artifacts produced by crossta...
Article -
6
Clinical evaluation of the novel digital liquid chip method for anti-dsDNA detection in SLE
Published 2025-07-01Get full textObjective This study aims to evaluate the diagnostic performance of the digital liquid chip method (DLCM) compared with indirect immunofluorescence (IIF) and chemiluminescent immunoassay (CLIA) for anti-double-stranded DNA (dsDNA) antibody detection in SLE.Methods The retrospective study consecutive...
Article -
7
Engineered Outer Membrane Vesicles for Antigen Delivery: Exploratory Study on Adjuvant Activity and Systemic Reactogenicity
Published 2025-05-01Get full textBackground: Outer Membrane Vesicles (OMVs), nanosized particles derived from Gram-negative bacteria, are promising vaccine carriers due to innate immunogenicity and self-adjuvant properties. Yet the systematic evaluations of OMV-associated toxicity remain limited. Methods: We developed a CRISPR/Cas9...
Article -
8
Exploring the biological basis for the identification of different syndromes in ischemic heart failure based on joint multi-omics analysis
Published 2025-07-01Get full textBackgroundIHF is a major chronic disease that seriously threatens human health. Qi deficiency and blood stasis syndrome (QDBS), Yang deficiency with blood stasis syndrome (YDBS) and Yang deficiency and blood stasis with fluid retention syndrome (YDBSFR) are the basic syndromes of IHF in Chinese medi...
Article