Search Results - Rui Wang

BackgroundSorafenib, a multi-kinase inhibitor, is a key therapeutic agent in the treatment of advanced hepatocellular carcinoma (HCC), metastatic renal cell carcinoma (RCC), and radioactive iodine-refractory differentiated thyroid cancer (DTC). However, its clinical efficacy is frequently hampered b...

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Identifying novel and functional RNA structures remains a significant challenge in RNA motif design and is crucial for developing RNA-based therapeutics. Here we introduce a computational topology-based approach with unsupervised machine-learning algorithms to estimate the database size and content...

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Metal–organic frameworks (MOFs) are a novel type of porous crystalline materials assembled from metal ions and organic linkers. Their derivatives can inherit characteristics such as high specific surface area, tunable porosity, and unique topological structures, which make MOF-derived metal oxides i...

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The study explores the features of spatiotemporal circles of residents’ daily walking. Through a survey of residents’ walking activity in 16 residential communities, the walking purpose, distance, time, and speed of different residents were analyzed, and the circles of residents’ walking activities...

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ObjectiveThis work aims to assess the impact of three nuclear power plants (NPPs) in Zhejiang Province on the levels of 90Sr in surrounding seafood, and to evaluate the associated health risks, providing a scientific basis for operational monitoring and contributing essential baseline data for nucle...

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Millimeter-wave massive MIMO can effectively improve the signal-to-noise ratio, but the high-dimensional channel matrix significantly increases the complexity of the classic channel estimation algorithm. On the other hand, millimeter-wave massive MIMO has low rank and sparsity properties in the angl...

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Remote sensing precipitation products are essential for the systematic analysis of precipitation characteristics and changes. This study conducts a comparative evaluation of precipitation products from rain gauge stations, Climate Prediction Center morphing technique (CMORPH), Tropical Rainfall Meas...

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Abstract Mass shootings in the U.S. have been at the center of the public crisis debate for a long time. Combining information on mass shootings with background check reports from the Federal Bureau of Investigation, this study applies mass shootings as exogenous shocks and reveals that the demand f...

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A new explanation has been proposed on the nature of the three-part (bright core, dark cavity, and bright front) structure of coronal mass ejections (CMEs). It suggests that the bright front originates from the plasma pileup along the overlying coronal loops rather than the boundary of the magnetic...

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ABSTRACT Objective Increased marrow fat fraction (MFF) of vertebrae was detected in patients with osteoporosis. However, MFF of the fractured vertebrae decreased significantly following the fracture. The aim of this study was to assess the predictive value of fractured vertebrae MFF quantified on T2...

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<b>Objectives</b>: (R)-ketamine hydrochloride injection is a novel, rapid-acting antidepressant for the treatment of treatment-resistant depression. The aim of this study was to assess the pharmacokinetics, safety, and tolerability of (R)-ketamine hydrochloride injection in healthy Chine...

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New types of light-emitting diode (LED) sources were applied to irradiate Botrytis cinerea mycelium and tomato leaves that were inoculated with B. cinerea to assess the effect of different LED light wavelengths on the infection of tomato with B. cinerea, to determine the optimum light wavelengths to...

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The combined effects of straw incorporation (SI) and polymer-coated urea (PCU) application on soil ammonia (NH3) and nitrous oxide (N2O) emissions from agricultural fields have not been comprehensively evaluated in Northwest China. We conducted a two-year field experiment to assess the effects of co...

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Fire poses a serious threat to the global economy, environment, and social stability, highlighting the need for rapid and accurate fire detection. Remote sensing combined with deep learning has outperformed traditional fire assessment methods. However, in early fire stages, small flame areas, class...

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<b>Objective:</b> Our objective was to explore the regulatory mechanism of salt processing on the metabolome of the raspberry and its potential efficacy against diabetic nephropathy (DN), providing metabolomic and network pharmacological evidence for the scientific connotation of traditi...

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Vascular dementia (VaD) ranks as the second most prevalent subtype of dementia, surpassed only by Alzheimer’s disease (AD). The maintenance of neurological function and cerebral homeostasis critically depends on precisely regulated blood flow within the intricately organized cerebrovascular network....

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AimsTo investigate the relationship between liver function indices (AST, ALT, GGT) and inflammatory markers (CRP, white blood cell count) in multiple injury patients at different time points post-trauma.MethodsWe retrospectively analyzed 114 patients with multiple injuries admitted to a tertiary tra...

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ZSM⁃5 has been widely used in the field of petrochemical industry. The extensive use of organic templates in its conventional synthesis process has caused serious problems on environmental and cost. In this paper, the hydrothermal synthesis of ZSM⁃5 with tetraethyl orthosilicate, aluminum sulfate oc...

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