Torthaí cuardaigh - Reham M. Samra

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    Molecular Docking, Molecular Dynamics Simulation, and Pharmacophore-Based Virtual Screening Unveil Natural Compounds with TIM-3 Inhibitory Activity

    Molecular Docking, Molecular Dynamics Simulation, and Pharmacophore-Based Virtual Screening Unveil Natural Compounds with TIM-3 Inhibitory Activity de réir Abdulrahim A. Alzain, Mohammed A. Almogaddam, Rayan Yousif, Mohammed Hamed Alqarni, Ahmed I. Foudah, Wadah Osman, Khaled M. Elamin, Hagar M. Mohamed, Ehssan Moglad, Ahmed Ashour, Reham M. Samra, Gamal A. Mohamed, Sabrin R.M. Ibrahim

    Foilsithe / Cruthaithe 2025-06-01

    Introduction: The aberrant expression of T cell immunoglobulin mucin-3 (TIM-3) has been linked to adaptive immunotherapy resistance and poor prognosis. Targeting TIM-3 has gained popularity due to positive outcomes in preclinical settings. Materials and method: This research explored the Supernatura...

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