Suchergebnisse - R. Tan

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  1. 1

    Safety and pharmacokinetics of veliparib extended‐release in patients with advanced solid tumors: a phase I study von Theresa L. Werner, Jasgit Sachdev, Elizabeth M. Swisher, Martin Gutierrez, Muaiad Kittaneh, Mark N. Stein, Hao Xiong, Martin Dunbar, Danielle Sullivan, Philip Komarnitsky, Mark McKee, Antoinette R. Tan

    Veröffentlicht 2018-06-01

    Abstract The poly(ADP‐ribose) polymerase‐1/2 inhibitor veliparib is active against tumors deficient in homologous DNA damage repair. The pharmacokinetics and safety of veliparib extended‐release (ER) were evaluated in patients with advanced solid tumors. This phase I study assessed veliparib‐ER up t...

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  2. 2

    Effect of Subthreshold Nanosecond Laser on Loss of OCT Outer Retinal Bands in Age-Related Macular Degeneration: A LEAD Study Report von Robyn H. Guymer, MBBS, PhD, Joseph P.M. Blair, PhD, Sandro De Zanet, PhD, Stefanos Apostolopoulos, PhD, Carlos Ciller, PhD, Zhichao Wu, BAppSc(Optom), PhD, S. Al-Qureshi, L. Busija, I. Constable, D. Louis, C. Harper, S. Wickremasinghe, P. Van Wijngaarden, L. Lim, S. Durkin, J. Runciman, J. Gihotra, J. Muecke, K. Haywood, C. Brko, J. Paley, M. Smith, C. Luscombe, R. Vincent, D. Lee, R.H. Guymer, C. Luu, Z. Wu, L.A.B. Hodgson, K. Brassington, E. Caruso, M. McGuinness, N. Tindill, K.Z. Aung, E. Baglin, P. Sharangan, C.A. Harper, S. Wickremasinghe, L. Lim, P. Van Wijngaarden, S. Sandhu, T. Nguyen, A. Cohn, D. Qatarneh, L. Robman, G. Makeyeva, R. Tan, S. Taori, K. Creese, M. Chen, D. Ong, S. No, R. Kandasamy, S.W. Lim, M. Okada, D. Cugley, R. O'Day, P. Keller, K. Lee, E. Alessandrello, J. Alessi-Calandro, M. Kolic, T. Wu, S. Griffin, J.J. Lek, W. Heriot, X. Fagan, R. McIntosh, C. Lowe, J. Boyle, O. Shanahan, F. Chen, I. McAllister, T. Isaacs, A. Shaw, C. Balarantnasingam, Y. Chen, W. Cunningham, R. Viljoen, K. Kennelly, R. Blum, S. Arunachalam, H. Razavi, M. Adams, H. Brown, J. Bryant, R. Cowles, S. Radtke, C. Barry, E. Wong, F. Shilton, A. Soloshenko, A. Jason, A. Lin, A. McSweeney, A. King, B. Shalan, D. Xie, H. Vu, I. Tang, K. Mather, M. Cuypers, M. Cheng, R. McKeone, T. Busby, R. Matthews, G. Lingham, J. Arnold, A. Luckie, D. Chan, J. Chang, T. Tan, L. Koh, H. Cass, R. Fitzsimons, T. Forsyth, A. Nguyen, V. Ghebrial, H. Ayson, A. Graham, M. Firibaldi, U. Chakravarthy, L. Kelly, K. Gillvray, M. Williams, G. Casalino, G. Mangoris, R. Das, T. Peto, L. Toth, M. Quinn, R. Denham, N.J. Lavery, G. Sterrett, V. Silvestri, G. Young, K. Graham, J. Keenan, L. Doyle, T. Douglas, D. Burns, P. Wright, L. Scullion

    Veröffentlicht 2025-11-01

    Purpose: To evaluate the effect of subthreshold nanosecond laser (SNL) treatment on the rate of loss of the OCT outer retinal bands in intermediate age-related macular degeneration (AMD). Design: Post hoc analysis of the Laser Intervention in the Early Stages of AMD (LEAD) study. Participants: A sub...

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