Search Results - R. S. Karpov

The article presents the analysis of the creative heritage of the outstanding physician, teacher, scientist, Academician of the USSR Academy of Medical Sciences D.D. Yablokov in connection with the 120th anniversary of his birth.

The article presents the understanding of scientific heritage of the prominent Russian clinician, founder of the Siberian school of physicians, Academician D.D. Yablokov, whose 110th jubilee took place on November of 2006.

In this lecture there is the information about historical steps of fundamental researches of pathogenesis of atherosclerosis, about biochemical, immunological and genetic abnormalities. Significance of x-ray, radionuclide methods in diagnosis of vascular affection is shown. The achievements of nowad...

Full description

Interview with academician R.S. Karpov

Aim. To study diagnostic and prognostic role of hyperglycemia in patients with acute phase of myocardial infarction (MI), according to five-year follow(up results. Material and methods. In total, 130 men aged 47,1±1,7 years were examined. In 75 patients, glucose level in venous blood was measured du...

Full description

While planning treatment and prevention in cardiovascular disorders (CVD) it is important to take into account the data on stability of clinical course of the main risk factors (RF). Until recently there is no such data on Russian population. Aim. To study the stability of arterial hypertension (AH)...

Full description

Peculiarities in the structure of mortality of people living in the Tomsk Region have been revealed, and main ways to decrease the mortality have been determined. In 2002 the death rate in the Tomsk Region was 14.3 per 1000 people, which is lower than the average Russian death rate (16.3). The analy...

Full description

Aim. To study the safety, lipid-lowering effectiveness, and anti-inflammatory activity of three-month therapy with generic atorvastatin (Atomax) in patients with high cardiovascular risk and dyslipidemia (DLP).Material and methods. The study included 36 DLP patients: Group I (n=17) with coronary hea...

Full description

The role of the alcoholic factor in structure of death rate of the population of Tomsk area is studied. At pathology-anatomic research alcohol in blood was found out in 38,9% of cases. This parameter remains rather stable during of some years while death rate from a poisoning with ethyl spirit last...

Full description

Starting from 1992, the demographic situation in the Tomsk Region is characterized by a decrease of the population. It is mostly affected by the natural migration of population. The tendency of increase (decrease) in the birth rate is mostly determined by the past period. Thus, from 2000, the stable...

Full description

The aim of the study. Based on the data of the Register of new cases of hospital pulmonary embolism (PE) in hospitals in Tomsk (2003–2012), to explore the contribution of obesity to the development of venous thromboembolism.Material and Methods. Study were subjected to medical history and records of...

Full description

Aim. To study the prognostic significance of cardiovascular risk factors (RFs) in the formation of all-cause and cardiovascular mortality based on the results of a 27-year prospective cohort study of Tomsk population of both sexes aged 20-59 years.Material and methods. The object of study was random...

Full description

The article analyzes a comparative efficacy of pharmacoinvasive reperfusion and primary percutaneous intervention in patients with ST elevation acute myocardial infarction in real clinical practice with fulfillment of Guidelines for the “first-medical-contact — balloon time”. The problem of choice i...

Full description

Aim. To compare the effectiveness of three variants of long-term combination antihypertensive therapy (AHT), based on two methods of renin-angiotensinaldosterone system (RAAS) inhibition (angiotensin-converting enzyme inhibitors (ACEI) or angiotensin II receptor antagonists (ARAII)) or on calcium ch...

Full description

Aim. To evaluate the efficacy of long-term combined antihypertensive therapy (AHT) based on renin-angiotensin-aldosterone system (RAAS) blockers, indapamide and calcium channel blocker (CCB) in hypertensive patients with diabetes mellitus (DM) in accordance with target blood pressure (BP) <13...

Full description

Aim. To assess the changes in biomechanics of the heart at early stages post-acute ST-elevation myocardial infarction (MI) by 2D speckle tracking echocardiography.Material and methods. Totally, 35 patients included (mean age — 58,46±10,2 year old) with acute Q-MI admitted within 24 hours from the di...

Full description

Aim. To study the functional activity of T-helper subpopulations (pro-inflammatory T-helpers-17 (Th17) and T-helpers-1 (Th1) and immune-suppressing FoxP3+ T-regulators (Treg)) and its association with clinical parameters, glycemic control levels, and insulin resistance severity among patients with a...

Full description

Aim. To study the relationship of 24-hour BP patterns in patients with AH resistant to drug treatment and structural-functional changes in heart before and after sympathetic denervation of the kidneys.Material and methods. The study included 53 patients (25 women and 28 men) with a diagnosis of II s...

Full description

Aim. To study the interdependence of spousal body mass and influence of spouse overweight on the death risk according to the 27-year cohort prospective study.Material and methods. We examined a random household sample (n=1546; married couples, 427). Overweight frequency among spouses was studied on...

Full description

The review discusses an analysis of the literature on various aspects of the pathogenesis, diagnosis and treatment of vasospastic angina (VA). Data on the prevalence of coronary artery spasm (CAS) in various populations, as well as risk factors and triggers, are presented. We considered pathophysiol...

Full description